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Open AccessJournal ArticleDOI

The costs of traumatic brain injury: a literature review.

TLDR
Very little research has been published on the economic burden that mild and moderate traumatic brain injury patients pose to their families, careers, and society as a whole, and further research is needed to estimate the economicurden of these patients on healthcare providers and social services.
Abstract
OBJECTIVE: The purpose of this study was to review the literature relating to the psychosocial costs associated with traumatic brain injury (TBI). METHODS: Nine online journal databases, including MEDLINE, CINAHL, PsychINFO, and PUBMED, were queried for studies between July 2010 and May 2012 pertaining to the economic burden of head injuries. Additional studies were identified through searching bibliographies of related publications and using Google internet search engine. RESULTS: One hundred and eight potentially relevant abstracts were identified from the journal databases. Ten papers were chosen for discussion in this review. All but two of the chosen papers were US studies. The studies included a cost-benefit analysis of the implementation of treatment guidelines from the US brain trauma foundation and a cost-effectiveness analysis of post-acute traumatic brain injury rehabilitation. CONCLUSION: Very little research has been published on the economic burden that mild and moderate traumatic brain injury patients pose to their families, careers, and society as a whole. Further research is needed to estimate the economic burden of these patients on healthcare providers and social services and how this can impact current health policies and practices. Language: en

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Updated clinical practice guidelines for concussion/mild traumatic brain injury and persistent symptoms

TL;DR: A modified Delphi process was used to create 96 recommendations addressing the diagnosis and management of mTBI and persistent symptoms, including post-traumatic headache, sleep disturbances, mental health disorders, cognitive difficulties, vestibular and vision dysfunction, fatigue and return to activity/work/school.
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The bidirectional gut-brain-microbiota axis as a potential nexus between traumatic brain injury, inflammation, and disease.

TL;DR: This review article will attempt to connect the dots to reveal novel insights into the bidirectional influence of the gut-brain axis and propose a conceptual model relevant to the recovery from TBI and subsequent risk for future neurological conditions.
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Traumatic brain injury in the netherlands: Incidence, costs and disability-adjusted life years

TL;DR: The integrated approach of assessing incidence, costs and disease burden enables detection of important risk groups in TBI, development of prevention programs that target these risk groups and assessment of the benefits of these programs.
Journal ArticleDOI

The effect of concomitant peripheral injury on traumatic brain injury pathobiology and outcome

TL;DR: The findings of this review suggest that concomitant extracranial injuries are capable of modifying the outcomes and pathobiology of traumatic brain injury, in particular neuroinflammation.
Journal ArticleDOI

SNTF immunostaining reveals previously undetected axonal pathology in traumatic brain injury.

TL;DR: Supporting its use as a biomarker of DAI, SNTF immunoreactive axons were observed at all time points following both human severe TBI and in the model of mild TBI.
References
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Journal ArticleDOI

The impact of traumatic brain injuries: A global perspective

TL;DR: There is a large gap in data on incidence, risk factors, sequelae, financial costs, and social impact of TBI, and this should be addressed through planning of comprehensive TBI prevention programs in LMICs through well-established surveillance systems.
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Disability in young people and adults one year after head injury: prospective cohort study

TL;DR: The incidence of disability in young people and adults admitted with a head injury is higher than expected and reflects the high rate of sequelae previously unrecognised in the large number of patients admitted to hospital with an apparently mild head injury.
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Traumatic brain injury (TBI) 10?20 years later: a comprehensive outcome study of psychiatric symptomatology, cognitive abilities and psychosocial functioning

TL;DR: The results indicate that persons with TBI and their families may need professional assistance to maintain a reasonable psychosocial quality of life, even more than a decade post-injury.
Journal ArticleDOI

The five year outcome of severe blunt head injury: a relative's view.

TL;DR: Persisting severe deficits, in some cases worse than at 1 year, were primarily psychological and behavioural, although minor physical deficits, for example in vision, were also common.
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Late outcome of very severe blunt head trauma: a 10-15 year second follow-up.

TL;DR: Though physical impairment, dysarthria and defects of memory remained severe in many cases, the psychosocial sequelae presented the most serious problems and long-term improvement of functional state was common and several regained at least some work capacity.
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