Journal ArticleDOI
The strobilurin fungicides.
D. W. Bartlett,John Martin Clough,Jeremy Robert Godwin,Alison A. Hall,Mick Hamer,Bob Parr-Dobrzanski +5 more
Reads0
Chats0
TLDR
This review describes in detail the properties of the strobilurin active ingredients--their synthesis, biochemical mode of action, biokinetics, fungicidal activity, yield and quality benefits, resistance risk and human and environmental safety.Abstract:
Strobilurins are one of the most important classes of agricultural fungicide. Their invention was inspired by a group of fungicidally active natural products. The outstanding benefits they deliver are currently being utilised in a wide range of crops throughout the world. First launched in 1996, the strobilurins now include the world's biggest selling fungicide, azoxystrobin. By 2002 there will be six strobilurin active ingredients commercially available for agricultural use. This review describes in detail the properties of these active ingredients--their synthesis, biochemical mode of action, biokinetics, fungicidal activity, yield and quality benefits, resistance risk and human and environmental safety. It also describes the clear technical differences that exist between these active ingredients, particularly in the areas of fungicidal activity and biokinetics.read more
Citations
More filters
Journal ArticleDOI
The Unique Role of Fluorine in the Design of Active Ingredients for Modern Crop Protection
TL;DR: The complex structure–activity relationships associated with biologically active molecules mean that the introduction of fluorine can lead to either an increase or a decrease in the efficacy of a compound depending on its changed mode of action, physicochemical properties, target interaction, or metabolic susceptibility and transformation.
Journal ArticleDOI
Priming for Enhanced Defense
TL;DR: This review covers recent advances in disclosing molecular mechanisms of priming, which include elevated levels of pattern-recognition receptors and dormant signaling enzymes, transcription factor HsfB1 activity, and alterations in chromatin state.
Journal ArticleDOI
Contamination of vineyard soils with fungicides: a review of environmental and toxicological aspects.
Michael Komárek,Michael Komárek,Eva Čadková,Vladislav Chrastný,François Bordas,Jean-Claude Bollinger +5 more
TL;DR: The environmental and toxicological hazards associated with the extensive use of fungicides should be performed carefully according to the physico-chemical properties of the soils and climatic and hydrogeological characteristics of the vine-growing regions.
Journal ArticleDOI
Advances in understanding molecular mechanisms of fungicide resistance and molecular detection of resistant genotypes in phytopathogenic fungi
TL;DR: Recent advances in understanding of resistance mechanisms of phytopathogenic fungi to some major classes of fungicides at a molecular level and developments in molecular detection of fungicide-resistant fungi are reviewed.
Journal ArticleDOI
The cytochrome bc1 complex: function in the context of structure.
TL;DR: Recent advances in the understanding of the mechanism of the bc1 complex and their relation to physiologically important issues are reviewed in the context of the structural information available.
References
More filters
Journal ArticleDOI
Electron transfer by domain movement in cytochrome bc1.
Zhaolei Zhang,Li-Shar Huang,Li-Shar Huang,Vladimir M. Shulmeister,Young In Chi,Kyeong Kyu Kim,Li-Wei Hung,Antony R. Crofts,Edward A. Berry,Sung-Hou Kim,Sung-Hou Kim +10 more
TL;DR: X-ray crystal structures of the cytochrome bc1 complex from chicken, cow and rabbit in both the presence and absence of inhibitors of quinone oxidation, reveal two different locations for the extrinsic domain of one component of the enzyme, an iron–sulphur protein.
Journal ArticleDOI
Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.
TL;DR: The approach to crystallize membrane proteins as complexes with specific antibody fragments appears to be of general importance and reveals in detail the binding sites of the natural substrate coenzyme Q6 and the inhibitor stigmatellin.
Journal ArticleDOI
Strobilurins: Evolution of a New Class of Active Substances
TL;DR: A fungus that grows on pinecones yields a compound with antifungal activity that has become the natural model for a significant innovation in crop protection and is a fascinating success story.
Journal ArticleDOI
Bioregulatory effects of the fungicidal strobilurin kresoxim-methyl in wheat (Triticum aestivum)
Klaus Grossmann,Günter Retzlaff +1 more
TL;DR: In a series of biotests including heterotrophic maize and photoautotrophic algal cell suspensions, duckweed, isolated mustard shoots and germinating cress seeds, strobilurin kresoxim-methyl (BAS 490 F) was found to induce physiological and developmental alterations in wheat (Triticum aestivum L.) which are seen in connection with improved yield as mentioned in this paper.
Journal ArticleDOI
Oudemansin, strobilurin A, strobilurin B and myxothiazol: new inhibitors of the bc1 segment of the respiratory chain with an E-beta-methoxyacrylate system as common structural element.
TL;DR: The inhibitory action and binding characteristics of the new anti-fungal antibiotic myxothiazol has been described and a red shift of the ferrocytochrome b spectrum is indicated, independent of and differs from the antimycin red shift.