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The suicide prevention effect of lithium: more than 20 years of evidence—a narrative review

TLDR
A comprehensive review of studies investigating the anti-suicidal effect of lithium in patients with affective disorders finds that the use of lithium is still underrepresented.
Abstract
The management and treatment of patients with suicidal behavior is one of the most challenging tasks for health-care professionals. Patients with affective disorders are at high risk for suicidal behavior, therefore, should be a target for prevention. Numerous international studies of lithium use have documented anti-suicidal effects since the 1970s. Despite the unambiguous evidence of lithium’s anti-suicidal effects and recommendations in national and international guidelines for its use in acute and maintenance therapy of affective disorders, the use of lithium is still underrepresented. The following article provides a comprehensive review of studies investigating the anti-suicidal effect of lithium in patients with affective disorders.

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Citations
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Journal ArticleDOI

Global Lithium Sources—Industrial Use and Future in the Electric Vehicle Industry: A Review

TL;DR: In this article, a review of industrial uses of lithium is discussed along with a compilation of the locations of the main geological sources of lithium, with an emphasis on the use in lithium ion batteries and their use in the electric vehicle industry.
Journal ArticleDOI

Aggression in autism spectrum disorder: presentation and treatment options

TL;DR: Therapeutic strategies including functional behavioral assessment, reinforcement strategies, and functional communication training may have a significant impact in reducing the frequency and intensity of aggressive behavior in individuals with ASD.
Journal ArticleDOI

The use of lithium for the treatment of bipolar disorder: Recommendations from clinical practice guidelines.

TL;DR: This paper compared and synthesized recommendations for the treatment of bipolar disorder made by recognized CPGs internationally across multiple clinical issues, including clinical indications, disorder subtypes, additional uses, special populations, practical aspects, and side effects.
Journal ArticleDOI

Medication nonadherence in bipolar disorder: a narrative review.

TL;DR: Clinicians should routinely enquire about nonadherence in a nonjudgmental fashion and potential steps to improve adherence include simple pragmatic strategies related to prescribing including shared decision-making, psychoeducation with a clear focus on adherence and managing comorbid substance misuse and improving therapeutic alliance.
Journal ArticleDOI

Areas of uncertainties and unmet needs in bipolar disorders: clinical and research perspectives

TL;DR: There are several promising opportunities for improving treatment of bipolar disorder to deliver medical care that is more personalised, including improvement of adequate recognition and intervention in at-risk and early-disease stages, and identification of reliable warning signs and prevention of relapses in unstable and rapid cycling patients.
References
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Journal ArticleDOI

Randomized controlled trial.

Book

Bipolar Disorder

Journal ArticleDOI

Psychological autopsy studies of suicide: a systematic review.

TL;DR: In this paper, a systematic review aimed to examine the results of studies of suicide that used a psychological autopsy method, which offers the most direct technique currently available for examining the relationship between particular antecedents and suicide.
Journal Article

Psychological autopsy studies of suicide: a systematic review. (vol 33, pg 395, 2003)

TL;DR: The results indicated that mental disorder was the most strongly associated variable of those that have been studied and suicide prevention strategies may be most effective if focused on the treatment of mental disorders.
Book ChapterDOI

Randomized Controlled Trial

TL;DR: Attendance at these specialized prenatal clinics enhanced medical students’ comfort in talking with pregnant Native American women about the integrative roles of spiritual beliefs, tribal ceremonies and complementary medicine in their pregnancy outcome.
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