Thyroid disorders and diabetes mellitus.
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TLDR
Thyroid disorders can have a major impact on glucose control, and untreated thyroid disorders affect the management of diabetes in patients, so a systematic approach to thyroid testing in patients with diabetes is recommended.Abstract:
Studies have found that diabetes and thyroid disorders tend to coexist in patients. Both conditions involve a dysfunction of the endocrine system. Thyroid disorders can have a major impact on glucose control, and untreated thyroid disorders affect the management of diabetes in patients. Consequently, a systematic approach to thyroid testing in patients with diabetes is recommended.read more
Citations
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Journal ArticleDOI
Prevalence of thyroid dysfunction in patients with diabetes mellitus.
Cátia Cristina Silva Sousa Vergara Palma,Marco Pavesi,Verônica G. Nogueira,Eliete L.S. Clemente,Maria de Fátima Bevilacqua Motta Pereira Vasconcellos,Luiz Carlos Pereira,Fernanda Faissol Pacheco,Tassia Gomide Braga,Ludmila de Faria Bello,Juliana Soares,Stefanie Cathren Fenizola dos Santos,Vinícius Paes Leme Cavalcante Campos,Marília B. Gomes +12 more
TL;DR: Screening for thyroid disease among patients with diabetes mellitus should be routinely performed considering the prevalence of new cases diagnosed and the possible aggravation the classical risk factors such as hypertension and dyslipidemia, arising from an undiagnosed thyroid dysfunction.
Journal ArticleDOI
Associated autoimmune diseases in children and adolescents with type 1 diabetes mellitus (T1DM)
TL;DR: The present review reports on the classification of autoimmune diabetes, and on the prevalence, pathogenesis, predictive factors and clinical presentation of pancreatic autoimmunity and of all associated autoimmune disorders in children with T1DM.
Journal ArticleDOI
Thyroid autoimmunity as a window to autoimmunity: An explanation for sex differences in the prevalence of thyroid autoimmunity.
TL;DR: The ability of the thyrocytes to participate in innate immunity through the TLR provides an adjuvant-like signal and allows for the action of other agents, such as environmental factors, viruses, bacteria, and even stress to provide the initiation step to break tolerance to thyroid self-antigens.
Journal ArticleDOI
Methylglyoxal - An emerging biomarker for diabetes mellitus diagnosis and its detection methods.
Lakshmishri Ramachandra Bhat,Srinivasan Vedantham,Uma Maheswari Krishnan,John Bosco Balaguru Rayappan +3 more
TL;DR: The function of MG and detection strategies are correlated to explain the major challenges posed towards implementation of easy, efficient and accurate standardization.
Journal ArticleDOI
Thyroid Dysfunction and Type 2 Diabetes Mellitus: Screening Strategies and Implications for Management
TL;DR: Thyrovigilance in T2DM patients and diabetovigilation in TD patients may therefore be necessary to facilitate individualized care and management.
References
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Journal ArticleDOI
Serum TSH, T4, and Thyroid Antibodies in the United States Population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)
Joseph G. Hollowell,Norman W. Staehling,W. Dana Flanders,W. Harry Hannon,Elaine W. Gunter,Carole A. Spencer,Lewis E. Braverman +6 more
TL;DR: TSH and the prevalence of antithyroid antibodies are greater in females, increase with age, and are more in whites and Mexican Americans than in blacks, which needs more research to relate these findings to clinical status.
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The Colorado Thyroid Disease Prevalence Study
TL;DR: The results confirm that thyroid dysfunction is common, may often go undetected, and may be associated with adverse health outcomes that can be avoided by serum TSH measurement.
Journal ArticleDOI
The spectrum of thyroid disease in a community: the whickham survey
W.M.G. Tunbridge,D. C. Evered,Reginald Hall,D. Appleton,M Brewis,F. Clark,J G Evans,E. T. Young,T. Bird,P. A. Smith +9 more
TL;DR: TSH levels above 6 mu/1 were shown to reflect a significant lowering of circulating thyroxine levels and showed a strong association with thyroid antibodies in both sexes, independent of age.
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Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity
Christian Vaisse,Karine Clément,Emmanuelle Durand,Serge Hercberg,Bernard Guy-Grand,Philippe Froguel +5 more
TL;DR: It is demonstrated that MC4-R mutations are a frequent but heterogeneous genetic cause of morbid obesity and transmission in the families of the carriers indicates a variable expressivity that is not related to the functional severity of the mutations.
Journal ArticleDOI
Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
Miguel López,Miguel López,Luis M. Varela,María J. Vázquez,Sergio Rodriguez-Cuenca,Carmen R. González,Vidya Velagapudi,Donald A. Morgan,Erik Schoenmakers,Khristofor Agassandian,Ricardo Lage,Pablo B. Martínez de Morentin,Sulay Tovar,Rubén Nogueiras,David Carling,Christopher J. Lelliott,Rosalía Gallego,Matej Orešič,Krishna Chatterjee,Asish K. Saha,Kamal Rahmouni,Carlos Dieguez,Antonio Vidal-Puig +22 more
TL;DR: Thyroid hormone–induced modulation of AMPK activity and lipid metabolism in the hypothalamus is a major regulator of whole-body energy homeostasis.