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Tuberculosis of spine

TLDR
It is a challenge to treat MDR-TB Spine with late onset paraplegia and progressive deformity and Physicians must treat tuberculosis of spine on the basis of Culture and sensitivity.
Abstract
Tuberculosis of the spine is one of the most common spine pathology in India. Over last 4 decades a lot has changed in the diagnosis, medical treatment and surgical procedures to treat this disorder. Further developments in diagnosis using molecular genetic techniques, more effective antibiotics and more aggressive surgical protocols have become essential with emergence of multidrug resistant TB. Surgical procedures such as single stage anterior and posterior stabilization, extrapleral dorsal spine anterior stabilization and endoscopic thoracoscopic surgeries have reduced the mortality and morbidity of the surgical procedures. is rapidly progressing. It is a challenge to treat MDR-TB Spine with late onset paraplegia and progressive deformity. Physicians must treat tuberculosis of spine on the basis of Culture and sensitivity.

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Journal ArticleDOI

Spinal tuberculosis: A review

TL;DR: For example, spinal tuberculosis is a destructive form of tuberculosis that causes the destruction of the intervertebral disk space and the adjacent vertebral bodies, collapse of the spinal elements, and anterior wedging leading to kyphosis and gibbus formation as mentioned in this paper.
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Tuberculosis of the spine: a fresh look at an old disease.

TL;DR: The dismal outcome of tuberculosis of the spine in the pre-antibiotic era has improved significantly because of the use of potent antitubercular drugs, modern diagnostic aids and advances in surgical management.
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Bone and joint tuberculosis.

TL;DR: Spinal tuberculosis is still a relative common extra spinal manifestation of spinal tuberculosis that requires a high degree of suspicion in order to avoid neurological complications and need of surgery.
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Spinal Tuberculosis: Current Concepts:

TL;DR: Improper dosing, inadequate duration of treatment, and inappropriate selection of candidates for chemotherapy has not only resulted in the resurgence of TB but also led to the most dreadful consequence of multidrug resistant strains.
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Tuberculosis of the spine. A systematic review of case series

TL;DR: Spinal TB is still an important public health issue, it must be suspected in the presence of back pain or characteristic images and should be confirmed with microbiological procedures, and there is heterogeneity in the percentage of patients treated by surgery.
References
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Journal ArticleDOI

Extrapulmonary tuberculosis in the united states

TL;DR: A retrospective survey of extrapulmonary tuberculosis has shown that it differs from pulmonary tuberculosis with regard to sex and race distribution, diagnosing physician's speciality and proportion of cases bacteriologically confirmed.
Journal Article

Controlling tuberculosis in the United States. Recommendations from the American Thoracic Society, CDC, and the Infectious Diseases Society of America.

TL;DR: In this statement, the American Thoracic Society, CDC, and the Infectious Diseases Society of America propose recommendations to improve the control and prevention of TB in the United States and to progress toward its elimination.
Journal ArticleDOI

Granulomatous inflammation--a review.

TL;DR: The initiation and development of granulomatous inflammation is discussed, stressing the importance of persistence of the inciting agent and the complex role of the immune system, not only in the perpetuation of the granulOMatous response but also in the development of necrosis and fibrosis.
Journal ArticleDOI

Results of treatment of spinal tuberculosis by " middle-path" regime

TL;DR: The efficacy of modern drugs in the treatment of tuberculosis of the spine has been evaluated by a personal follow-up for three to ten years and it is suggested that treatment should in the first place be by modern antitubercular drugs.
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Physicians must treat tuberculosis of spine on the basis of Culture and sensitivity.