Journal ArticleDOI
Understanding weight gain at menopause
Susan R. Davis,Camil Castelo-Branco,Peter Chedraui,Mary Ann Lumsden,Rossella E. Nappi,D. Shah,P. Villaseca +6 more
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TLDR
There is strong evidence that estrogen therapy may partly prevent this menopause-related change in body composition and the associated metabolic sequelae and further studies are required to identify the women most likely to gain metabolic benefit from menopausal hormone therapy in order to develop evidence-based clinical recommendations.Abstract:
Objective The aim of this review was to summarize the literature regarding the impact of the menopause transition on body weight and body composition.Methods We conducted a search of the literature...read more
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2016 IMS Recommendations on women’s midlife health and menopause hormone therapy
TL;DR: In preparing these international recommendations, experts have taken into account geographical variations in medical care, prevalence of diseases, and country-specific attitudes of the public, medical community and health authorities towards menopause management.
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Estrogen Deficiency and the Origin of Obesity during Menopause.
TL;DR: A systematic review discusses the role of estrogens and estrogen receptors in adipocyte differentiation, and its control by the central nervous systemn and the possible role of estrogen-like compounds and endocrine disruptors chemicals are discussed.
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Estrogen: a master regulator of bioenergetic systems in the brain and body.
TL;DR: By generating biomarker profiles that encompass peripheral metabolic changes occurring with menopause, individual risk profiles for decreased brain bioenergetics and cognitive decline can be created.
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Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association
Samar R. El Khoudary,Brooke Aggarwal,Theresa M. Beckie,Howard N. Hodis,Amber E. Johnson,Robert Langer,Marian C. Limacher,JoAnn E. Manson,Marcia L. Stefanick,Matthew A. Allison +9 more
TL;DR: The reported findings underline the significance of the MT as a time of accelerating CVD risk, thereby emphasizing the importance of monitoring women's health during midlife, a critical window for implementing early intervention strategies to reduce CVDrisk.
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Symptoms of menopause — global prevalence, physiology and implications
TL;DR: The goal of this Review is to describe in a timely manner new research findings on the global prevalence and physiology of menopausal symptoms and their impact on future health.
References
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Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.
William C. Knowler,Elizabeth Barrett-Connor,Sarah E. Fowler,Richard F. Hamman,John M. Lachin,Elizabeth A. Walker,David M. Nathan +6 more
TL;DR: In this paper, the authors compared a lifestyle intervention with metformin to prevent or delay the development of Type 2 diabetes in nondiabetic individuals. And they found that the lifestyle intervention was significantly more effective than the medication.
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Prevalence and trends in obesity among US adults, 1999-2008.
TL;DR: The increases in the prevalence of obesity previously observed do not appear to be continuing at the same rate over the past 10 years, particularly for women and possibly for men.
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Overweight, Obesity, and Depression A Systematic Review and Meta-analysis of Longitudinal Studies
Floriana S. Luppino,Leonore de Wit,Paul F. Bouvy,Theo Stijnen,Pim Cuijpers,Brenda W.J.H. Penninx,Frans G. Zitman +6 more
TL;DR: A reciprocal link between depression and obesity was found to increase the risk of depression, most pronounced among Americans and for clinically diagnosed depression, in addition to depression being predictive of developing obesity.
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Subcutaneous and visceral adipose tissue : Their relation to the metabolic syndrome
TL;DR: Methods for assessment of several phenotypes of human obesity, with special reference to abdominal fat content, have been evaluated and the endocrine regulation of abdominal visceral fat in comparison with the adipose tissue localized in other areas is presented.