Abigail M. Fellows

TL;DR: Natural scene VR provided relaxation both objectively and subjectively, and scene preference had a significant effect on mood and perception of scene quality, and VR may enable relaxation for people living in isolated confined environments, particularly when matched to personal preferences.

TL;DR: It is demonstrated that the affinity of the CAL PDZ domain for the CFTR C-terminus is much weaker than those of NherF1 and NHERF2 domains, enabling wild-type CFTR to avoid premature entrapment in the lysosomal pathway.

TL;DR: RNA interference targeting endogenous CAL specifically increases cell-surface expression of the disease-associated DeltaF508-CFTR mutant and thus enhances transepithelial chloride currents in a polarized human patient bronchial epithelial cell line, establishing CAL as a candidate therapeutic target for correction of post-maturational trafficking defects in cystic fibrosis.

TL;DR: Intraocular pressure results are consistent with the hypothesis that hydrostatic gradients affect IOP, and may explain how IOP can increase beyond supine values in microgravity when central venous and intracranial pressure do not.

TL;DR: Hearing deficits in HIV+ individuals could be a CNS side effect of HIV infection, certain ART regimen might produce CNS side effects that manifest themselves as hearing difficulties, and/or some ART regimens may treat CNS HIV inadequately, perhaps due to insufficient CNS drug levels, which is reflected as a central hearing deficit.