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Alain Coletta
Researcher at Université libre de Bruxelles
Publications - 13
Citations - 1389
Alain Coletta is an academic researcher from Université libre de Bruxelles. The author has contributed to research in topics: Bioconductor & Feature selection. The author has an hindex of 9, co-authored 13 publications receiving 1147 citations. Previous affiliations of Alain Coletta include University of Manchester & Vrije Universiteit Brussel.
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Journal ArticleDOI
A Survey on Filter Techniques for Feature Selection in Gene Expression Microarray Analysis
Cosmin Lazar,Jonatan Taminau,Stijn Meganck,David Steenhoff,Alain Coletta,Colin Molter,V. de Schaetzen,Robin Duque,Hugues Bersini,Ann Nowé +9 more
TL;DR: This survey focuses on filter feature selection methods for informative feature discovery in gene expression microarray (GEM) analysis, which is also known as differentially expressed genes (DEGs) discovery, gene prioritization, or biomarker discovery, and presents them in a unified framework.
Journal ArticleDOI
Batch effect removal methods for microarray gene expression data integration: a survey
Cosmin Lazar,Stijn Meganck,Jonatan Taminau,David Steenhoff,Alain Coletta,Colin Molter,David Y. Weiss-Solis,Robin Duque,Hugues Bersini,Ann Nowé +9 more
TL;DR: Methods designed to combine genomic data recorded from microarray gene expression (MAGE) experiments are reviewed in a unified framework together with a wide range of evaluation tools, which are mandatory in assessing the efficiency and the quality of the data integration process.
Journal ArticleDOI
Low-complexity regions within protein sequences have position-dependent roles.
Alain Coletta,Alain Coletta,John W. Pinney,David Y. Weiss Solís,David Y. Weiss Solís,James Marsh,Steve Pettifer,Teresa K. Attwood +7 more
TL;DR: The results suggest not only that LCRs may be involved in flexible binding associated with specific functions, but also that their positions within a sequence may be important in determining both their binding properties and their biological roles.
Journal ArticleDOI
The PRINTS database: a fine-grained protein sequence annotation and analysis resource--its status in 2012.
Teresa K. Attwood,Alain Coletta,Gareth Muirhead,Athanasia Pavlopoulou,Peter B. Philippou,Ivan Popov,Carlos Romá-Mateo,Athina Theodosiou,Alex L. Mitchell +8 more
TL;DR: The PRINTS database, now in its 21st year, houses a collection of diagnostic protein family ‘fingerprints’, whose unique inter-relationships provide distinctive signatures for particular protein families and structural/functional domains, and a number of recent developments are introduced.
Journal ArticleDOI
Unlocking the potential of publicly available microarray data using inSilicoDb and inSilicoMerging R/Bioconductor packages
Jonatan Taminau,Stijn Meganck,Cosmin Lazar,David Steenhoff,Alain Coletta,Colin Molter,Robin Duque,Virginie de Schaetzen,David Y. Weiss Solís,Hugues Bersini,Ann Nowé +10 more
TL;DR: The newly released inSilicoMerging R/Bioconductor package allows consistent retrieval, integration and analysis of publicly available microarray gene expression data sets and enables researchers to fully explore the potential of combining gene expressionData for downstream analysis.