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Alexis Criscuolo
Researcher at Pasteur Institute
Publications - 89
Citations - 4496
Alexis Criscuolo is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 25, co-authored 77 publications receiving 3218 citations. Previous affiliations of Alexis Criscuolo include Centre national de la recherche scientifique & University of Montpellier.
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Journal ArticleDOI
BMGE (Block Mapping and Gathering with Entropy): a new software for selection of phylogenetic informative regions from multiple sequence alignments
TL;DR: Simulation analyses show that the character trimming performed by BMGE produces datasets leading to accurate trees, especially with alignments including distantly-related sequences.
Journal ArticleDOI
Whole genome-based population biology and epidemiological surveillance of Listeria monocytogenes
Alexandra Moura,Alexis Criscuolo,Hannes Pouseele,Mylène M. Maury,Alexandre Leclercq,Alexandre Leclercq,Cheryl L. Tarr,Jonas T. Björkman,Timothy J. Dallman,Aleisha Reimer,Vincent Enouf,Elise Larsonneur,Heather A. Carleton,Hélène Bracq-Dieye,Hélène Bracq-Dieye,Lee S. Katz,Louis Jones,Marie Touchon,Mathieu Tourdjman,Matthew G. Walker,Steven Stroika,Thomas Cantinelli,Viviane Chenal-Francisque,Zuzana Kucerova,Eduardo P. C. Rocha,Celine Nadon,Kathie Grant,Eva Møller Nielsen,Bruno Pot,Peter Gerner-Smidt,Marc Lecuit,Sylvain Brisse +31 more
TL;DR: This work demonstrates the urgent need to monitor Lm strains at the global level and provides the unified approach needed for global harmonization of Lm genome-based typing and population biology.
Journal ArticleDOI
Uncovering Listeria monocytogenes hypervirulence by harnessing its biodiversity
Mylène M. Maury,Mylène M. Maury,Mylène M. Maury,Yu Huan Tsai,Yu Huan Tsai,Caroline Charlier,Marie Touchon,Marie Touchon,Viviane Chenal-Francisque,Viviane Chenal-Francisque,Alexandre Leclercq,Alexandre Leclercq,Alexis Criscuolo,Charlotte Gaultier,Charlotte Gaultier,Sophie Roussel,Anne Brisabois,Olivier Disson,Olivier Disson,Eduardo P. C. Rocha,Eduardo P. C. Rocha,Sylvain Brisse,Sylvain Brisse,Marc Lecuit +23 more
TL;DR: This study integrated human epidemiological and clinical data with bacterial population genomics to harness the biodiversity of the model foodborne pathogen Listeria monocytogenes and decipher the basis of its neural and placental tropisms.
Journal ArticleDOI
Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda.
Aline Uwimana,Eric Legrand,Barbara H. Stokes,Jean-Louis Mangala Ndikumana,Marian Warsame,Noella Umulisa,Daniel Ngamije,Tharcisse Munyaneza,Jean-Baptiste Mazarati,Kaendi Munguti,Pascal Campagne,Alexis Criscuolo,Frédéric Ariey,Monique Murindahabi,Pascal Ringwald,David A. Fidock,Aimable Mbituyumuremyi,Didier Menard +17 more
TL;DR: Identification in Rwanda of mutations in Plasmodium falciparum capable of conferring in vitro resistance to artemisinin, an essential medicine for the treatment of malaria, underscore the crucial need for surveillance in Africa to safeguard efficacy of life-saving therapies.
Journal ArticleDOI
Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis
Philip Supply,Michael Marceau,Sophie Mangenot,David Roche,David Roche,Carine Rouanet,Varun Khanna,Laleh Majlessi,Laleh Majlessi,Alexis Criscuolo,Julien Tap,Alexandre Pawlik,Laurence Fiette,Mickael Orgeur,Michel Fabre,Cecile Parmentier,Wafa Frigui,Roxane Simeone,Eva C. Boritsch,Anne-Sophie Debrie,Eve Willery,Danielle Walker,Michael A. Quail,Laurence Ma,Christiane Bouchier,Gregory Salvignol,Gregory Salvignol,Fadel Sayes,Fadel Sayes,Alessandro Cascioferro,Torsten Seemann,Valérie Barbe,Camille Locht,Maria-Cristina Gutierrez,Claude Leclerc,Claude Leclerc,Stephen D. Bentley,Timothy P. Stinear,Sylvain Brisse,Claudine Médigue,Claudine Médigue,Julian Parkhill,Stéphane Cruveiller,Stéphane Cruveiller,Roland Brosch +44 more
TL;DR: It is concluded that M. tuberculosis emerged from an ancestral STB-like pool of mycobacteria by gain of persistence and virulence mechanisms, and insights into the molecular events involved are provided.