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Andrew J. Alpert
Researcher at Purdue University
Publications - 14
Citations - 2636
Andrew J. Alpert is an academic researcher from Purdue University. The author has contributed to research in topics: Hydrophilic interaction chromatography & Ion chromatography. The author has an hindex of 10, co-authored 12 publications receiving 2511 citations.
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Hydrophilic-interaction chromatography for the separation of peptides, nucleic acids and other polar compounds
TL;DR: Hydrophilic-interaction chromatography fractionations resemble those obtained through partitioning mechanisms, and the chromatography of DNA, in particular, resembles the partitioning observed with aqueous two-phase systems based on polyethylene glycol and dextran solutions.
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Hydrophilic-interaction chromatography of complex carbohydrates
Andrew J. Alpert,Mukta M. Shukla,Ashok K. Shukla,Lynn R. Zieske,Sylvia W. Yuen,Michael A. J. Ferguson,Angela Mehlert,Markus Pauly,Ron Orlando +8 more
TL;DR: Complex carbohydrates can frequently be separated using hydrophilic-interaction chromatography (HILIC), which is promising for a variety of analytical and preparative applications.
Journal ArticleDOI
Preparation of a porous microparticulatee anion-exchange chromatography support for proteins
Andrew J. Alpert,Fred E. Regnier +1 more
TL;DR: In this paper, a hydrophilic, durable anion-exchange material has been developed for high performance liquid chromatography of proteins, where polyethyleneimine and simpler amines are adsorbed to porous, microparticulate silicas.
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Cation-exchange chromatography of peptides on poly(2-sulfoethyl aspartamide)-silica
TL;DR: The new cation exchanger is quite promising as a supplement to RPC for general peptide chromatography, with modest mixed-mode effects, allowing the resolution of peptides having identical charges at a given pH.
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High-performance hydrophobic-interaction chromatography of proteins on a series of poly(alkyl aspart-amide)-silicas
TL;DR: A series of bonded poly(alkyl aspartamide) coatings was prepared on silica and evaluated for highperformance hydrophobic-interaction chromatography (HPHIC) of proteins as mentioned in this paper.