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Anthony V. Nicola
Researcher at Washington State University
Publications - 42
Citations - 1270
Anthony V. Nicola is an academic researcher from Washington State University. The author has contributed to research in topics: Viral entry & Herpes simplex virus. The author has an hindex of 17, co-authored 42 publications receiving 1058 citations. Previous affiliations of Anthony V. Nicola include Virginia Commonwealth University & Westport Innovations.
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Journal ArticleDOI
Monoclonal Antibodies to Distinct Sites on Herpes Simplex Virus (HSV) Glycoprotein D Block HSV Binding to HVEM
Anthony V. Nicola,Manuel Ponce de Leon,Ruliang Xu,Wangfang Hou,J. Charles Whitbeck,Claude Krummenacher,Rebecca I. Montgomery,Patricia G. Spear,Roselyn J. Eisenberg,Gary H. Cohen +9 more
TL;DR: It is demonstrated that purified HSV-1 KOS virions bind directly to a soluble, truncated form of HVEM (HVEMt) in the absence of any other cell-associated components, and the mechanism of neutralization by these MAbs is via interference with the interaction between gD in the virus and HV EM on the cell.
Journal ArticleDOI
Virus Entry by Endocytosis
TL;DR: This review focuses on the cell biology of virus entry and the different strategies and endocytic mechanisms used by animal viruses.
Journal ArticleDOI
Functional region IV of glycoprotein D from herpes simplex virus modulates glycoprotein binding to the herpesvirus entry mediator.
Ann H. Rux,Sharon H. Willis,Anthony V. Nicola,Wangfang Hou,Charline Peng,Huan Lou,Gary H. Cohen,Roselyn J. Eisenberg +7 more
TL;DR: Examining other forms of gD, especially ones with mutations in region IV, suggest that residues between 234 and 275 are important for maintaining stability of the gDt-HveAt complex and that functional region IV is important for modulating the binding of g D to HveA.
Journal ArticleDOI
Unraveling a three-step spatiotemporal mechanism of triggering of receptor-induced Nipah virus fusion and cell entry.
Qian Liu,Jacquelyn A. Stone,Birgit Bradel-Tretheway,Jeffrey Dabundo,Javier A. Benavides Montano,Javier A. Benavides Montano,Jennifer Santos-Montanez,Scott B. Biering,Anthony V. Nicola,Ronald M. Iorio,Xiaonan Lu,Hector C. Aguilar +11 more
TL;DR: This work presents a comprehensive and fundamentally conserved mechanistic model of paramyxovirus membrane fusion triggering and cell entry, involving three spatiotemporally sequential cell receptor-induced conformational steps in NiV-G: two in the head and one in the stalk.
Journal ArticleDOI
Herpesvirus Entry into Host Cells Mediated by Endosomal Low pH
TL;DR: This review details the impact of the mildly acidic milieu of endosomes on the entry of herpesviruses, with particular emphasis on herpes simplex virus 1 (HSV‐1).