B
Bogusław Maciejewski
Researcher at Curie Institute
Publications - 80
Citations - 4619
Bogusław Maciejewski is an academic researcher from Curie Institute. The author has contributed to research in topics: Radiation therapy & Cancer. The author has an hindex of 25, co-authored 78 publications receiving 4448 citations. Previous affiliations of Bogusław Maciejewski include Oklahoma State University Center for Health Sciences & UCLA Medical Center.
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Journal ArticleDOI
The hazard of accelerated tumor clonogen repopulation during radiotherapy.
TL;DR: It is suggested that, on average, clonogen repopulation in squamous cell carcinomas of the head and neck accelerates only after a lag period of the order of 4 +/- 1 weeks after initiation of radiotherapy and that a dose increment of about 0.6 Gy per day is required to compensate for this repopulating.
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Treatment volume and tissue tolerance
TL;DR: T tentative conclusions were drawn regarding the influence on "tolerance" doses of tissue organization and the volume of an organ irradiated and sigmoid dose response curves, which are sensitive to small increases in "biologically effective" dose.
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Dose fractionation and regeneration in radiotherapy for cancer of the oral cavity and oropharynx: tumor dose-response and repopulation.
TL;DR: Overall treatment time influenced strongly the probability of local tumor control and the general principle of radiotherapy should be to deliver the desired fractionated dose regimen without unnecessary interruptions and in the shortest time compatible with no reduction in dose below that tolerated by the late-responding normal tissues.
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The influence of the number of fractions and of overall treatment time on local control and late complication rate in squamous cell carcinoma of the larynx
TL;DR: Whereas the late complication rate depended significantly on dose per fraction, local tumor control depended strongly on overall treatment time.
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Time factor in postoperative radiotherapy: a multivariate locoregional control analysis in 868 patients.
Rafał Suwiński,Anna Sowa,Tomasz Rutkowski,Jerzy Wydmański,Rafal Tarnawski,Bogusław Maciejewski +5 more
TL;DR: It is assumed that a highly significant adverse influence of radiation treatment gaps on the rate of tumor control is consistent with rapid repopulation of cancer clonogenes during PRT, and that the duration of time interval surgery-PRT appeared, by contrast, only borderline significant for RFS.