B
Bradley Gehrs
Researcher at University of Oklahoma Health Sciences Center
Publications - 14
Citations - 1117
Bradley Gehrs is an academic researcher from University of Oklahoma Health Sciences Center. The author has contributed to research in topics: Lymphoma & Cancer cell. The author has an hindex of 7, co-authored 14 publications receiving 1070 citations. Previous affiliations of Bradley Gehrs include University of Alabama at Birmingham & University of Oklahoma.
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Journal ArticleDOI
Autoimmune hemolytic anemia
TL;DR: This review discusses the demographics, etiology, clinical presentation, laboratory evaluation, and treatment options of autoimmune hemolytic anemia, which includes warm AIHA, cold agglutinin syndrome, paroxysmal cold hemoglobinuria, mixed‐type AIH, and drug‐induced AIHA.
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Toll-like receptor 9 agonists promote cellular invasion by increasing matrix metalloproteinase activity
Melinda A. Merrell,Joanna M. Ilvesaro,Niko Lehtonen,Timo Sorsa,Bradley Gehrs,Eben L. Rosenthal,Dongquan Chen,Brit Shackley,Kevin W. Harris,Katri S. Selander +9 more
TL;DR: It is shown here that TLR9 protein is expressed in human breast cancer cells and clinical breast cancer samples and a new molecular target for cancer therapy is proposed, becauseTLR9 has not been associated with cancer invasiveness previously.
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Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition
Annamaria Rapisarda,Melinda G. Hollingshead,Badarch Uranchimeg,Carrie Bonomi,Suzanne Borgel,John Carter,Bradley Gehrs,Mark Raffeld,Robert J. Kinders,Ralph E. Parchment,Miriam R. Anver,Robert H. Shoemaker,Giovanni Melillo +12 more
TL;DR: Results strongly suggest that combination of anti–vascular endothelial growth factor antibodies with HIF-1 inhibitors is an attractive therapeutic strategy targeting in the hypoxic tumor microenvironment.
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EX VIVO EXPANDED HUMAN Vλ9Vδ2+ λδ-T CELLS MEDIATE INNATE ANTITUMOR ACTIVITY AGAINST HUMAN PROSTATE CANCER CELLS IN VITRO
TL;DR: This work has identified a CD2 mediated, interleukin-12 dependent signaling pathway that inhibits activation induced cell death in mitogen stimulated human λδ-T cells, and it is shown that this pathway is related to apoptosis in mice.
Journal Article
Intravascular large B-cell lymphoma with hemophagocytic syndrome (Asian variant) in a Caucasian Patient
Kar Ming Fung,Jennifer Holter Chakrabarty,William Kern,Hany Magharyous,Bradley Gehrs,Shibo Li +5 more
TL;DR: A case of intravascular B-cell lymphoma in a Caucasian patient associated with secondary hemophagocytic syndrome is reported, demonstrating the importance of high index of suspicion and astute histopathologic examination in recognition of this unusual clinical and pathologic combination.