B
Brenda Phillips
Researcher at University of Wisconsin-Madison
Publications - 19
Citations - 1048
Brenda Phillips is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Cancer & Internal medicine. The author has an hindex of 11, co-authored 17 publications receiving 864 citations.
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Journal ArticleDOI
Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses
Nicholas J. Roberts,Linping Zhang,Filip Janku,Amanda Collins,Ren Yuan Bai,Verena Staedtke,Anthony Rusk,David Tung,Maria Miller,Jeffrey James Roix,Kristen V. Khanna,Ravi Murthy,Robert S. Benjamin,Thorunn Helgason,Ariel D. Szvalb,Justin E. Bird,Sinchita Roy-Chowdhuri,Halle H. Zhang,Yuan Qiao,Baktiar O. Karim,Jennifer S. McDaniel,Amanda K. Elpiner,Alexandra Sahora,Joshua Lachowicz,Brenda Phillips,Avenelle I. Turner,Mary K. Klein,G. S. Post,Luis A. Diaz,Gregory J. Riggins,Nickolas Papadopoulos,Kenneth W. Kinzler,Bert Vogelstein,Chetan Bettegowda,Chetan Bettegowda,David L. Huso,Mary Varterasian,Saurabh Saha,Shibin Zhou +38 more
TL;DR: Clostridium novyi-NT targets aberrant tumor physiology and can produce a precise, robust, and reproducible antitumor response, and is shown to can precisely eradicate neoplastic tissues in selected patients.
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Preliminary evidence for biologic activity of toceranib phosphate (Palladia®) in solid tumours
Cheryl A. London,Tamra Mathie,Nicole Stingle,Craig A. Clifford,Siobhan Haney,Mary K. Klein,Linda Beaver,Kate Vickery,David M. Vail,Betsey Hershey,Susan Ettinger,Andrew Vaughan,Francisco J. Alvarez,Lorin Hillman,Mike Kiselow,Doug H. Thamm,Mary Lynn Higginbotham,Meredith Gauthier,Erika L. Krick,Brenda Phillips,Tracy Ladue,Pam Jones,Jeffery Bryan,Virginia L. Gill,Andrew Novasad,Lisa Fulton,Janet K. Carreras,C. J. McNeill,Carolyn J. Henry,Sarah Gillings +29 more
TL;DR: Preliminary evidence that toceranib exhibits CB in dogs with certain solid tumours is provided, although future prospective studies are necessary to define its true activity.
Journal ArticleDOI
Use of single-agent carboplatin as adjuvant or neoadjuvant therapy in conjunction with amputation for appendicular osteosarcoma in dogs
Brenda Phillips,Barbara E. Powers,William S. Dernell,Rod C. Straw,Chand Khanna,Gary S Hogge,David M. Vail +6 more
TL;DR: Carboplatin treatment improves the survival probability in dogs with appendicular OSA compared to amputation alone and remains an acceptable alternative to adjuvant treatment with cisplatin.
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Liposome-encapsulated doxorubicin (Doxil) and doxorubicin in the treatment of vaccine-associated sarcoma in cats.
Valerie J. Poirier,Douglas H. Thamm,Ilene D. Kurzman,K. Ann Jeglum,Ruthanne Chun,Joyce E. Obradovich,Maura G. O'Brien,Rogers M. Fred,Brenda Phillips,David M. Vail +9 more
TL;DR: This study showed that both DOX and LED are efficacious in the treatment of VAS and should be considered in the Treatment of this tumor.
Journal ArticleDOI
Efficacy and Toxicity of Paclitaxel (Taxol) for the Treatment of Canine Malignant Tumors
Valerie J. Poirier,A.E. Hershey,Kristine Burgess,Brenda Phillips,Michelle Turek,Lisa J. Forrest,L. Beaver,David M. Vail +7 more
TL;DR: The overall toxicity was unacceptable at the 165 mg/m2 dose and subsequent evaluations of paclitaxel in tumor-bearing dogs should a starting dose of 132 mg/ m2 i.v. every 3 weeks.