C
Carol J. Whelan
Researcher at University College London
Publications - 142
Citations - 7380
Carol J. Whelan is an academic researcher from University College London. The author has contributed to research in topics: Amyloidosis & AL amyloidosis. The author has an hindex of 31, co-authored 120 publications receiving 5116 citations. Previous affiliations of Carol J. Whelan include Royal Free London NHS Foundation Trust & St George's, University of London.
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Journal ArticleDOI
Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis.
Julian D. Gillmore,Mathew S. Maurer,Rodney H. Falk,Giampaolo Merlini,Thibaud Damy,Angela Dispenzieri,Ashutosh D. Wechalekar,John L. Berk,John L. Berk,Candida Cristina Quarta,Martha Grogan,Helen J. Lachmann,Sabahat Bokhari,Adam Castano,Sharmila Dorbala,Geoff B. Johnson,Andor W. J. M. Glaudemans,Tamer Rezk,Marianna Fontana,Giovanni Palladini,Paolo Milani,P.L Guidalotti,Katarina Flatman,Thirusha Lane,Frederick W. Vonberg,Carol J. Whelan,James C. Moon,Frederick L. Ruberg,Frederick L. Ruberg,Edward J. Miller,David F. Hutt,Bouke P. C. Hazenberg,Claudio Rapezzi,Philip N. Hawkins +33 more
TL;DR: Bone scintigraphy enables the diagnosis of cardiac ATTR amyloidosis to be made reliably without the need for histology in patients who do not have a monoclonal gammopathy, and proposes noninvasive diagnostic criteria that are applicable to the majority of patients with this disease.
Journal ArticleDOI
Noncontrast T1 mapping for the diagnosis of cardiac amyloidosis.
Theodoros D. Karamitsos,Stefan K. Piechnik,Sanjay M Banypersad,Marianna Fontana,Ntobeko A.B. Ntusi,Vanessa M Ferreira,Vanessa M Ferreira,Carol J. Whelan,Saul G. Myerson,Matthew D. Robson,Philip N. Hawkins,Stefan Neubauer,James C. Moon +12 more
TL;DR: Noncontrast T1 mapping has high diagnostic accuracy for detecting cardiac AL amyloidosis, correlates well with markers of systolic and diastolic dysfunction, and is potentially more sensitive for detecting early disease than LGE imaging.
Journal ArticleDOI
Prognostic Value of Late Gadolinium Enhancement Cardiovascular Magnetic Resonance in Cardiac Amyloidosis
Marianna Fontana,Silvia Pica,Patricia Reant,Amna Abdel-Gadir,Thomas A. Treibel,Sanjay M Banypersad,Viviana Maestrini,William Barcella,Stefania Rosmini,Heerajnarain Bulluck,Rabya Sayed,Ketna Patel,Shameem Mamhood,Chiara Bucciarelli-Ducci,Carol J. Whelan,Anna S Herrey,Helen J. Lachmann,Ashutosh D. Wechalekar,Charlotte Manisty,Eric B. Schelbert,Peter Kellman,Julian D. Gillmore,Philip N. Hawkins,James C. Moon +23 more
TL;DR: Transmural LGE is determined reliably by PSIR and represents advanced cardiac amyloidosis and the PSIR technique provides incremental information on outcome even after adjustment for known prognostic factors.
Journal ArticleDOI
A new staging system for cardiac transthyretin amyloidosis
Julian D. Gillmore,Thibaud Damy,Marianna Fontana,Matthew Hutchinson,Helen J. Lachmann,Ana Martinez-Naharro,Candida Cristina Quarta,Tamer Rezk,Carol J. Whelan,Esther Gonzalez-Lopez,Thirusha Lane,Janet A. Gilbertson,Dorota Rowczenio,Aviva Petrie,Philip N. Hawkins +14 more
TL;DR: This simple, universally applicable staging system stratifies patients with both ATTRwt and ATTRv amyloid cardiomyopathy into prognostic categories will be of value in the design of forthcoming clinical trials of novel amyloids-specific therapies.
Journal ArticleDOI
Native T1 mapping in transthyretin amyloidosis
Marianna Fontana,Sanjay M Banypersad,Thomas A. Treibel,Viviana Maestrini,Daniel Sado,Steven K White,Silvia Pica,Silvia Castelletti,Stefan K. Piechnik,Matthew D. Robson,Janet A. Gilbertson,Dorota Rowczenio,David F. Hutt,Helen J. Lachmann,Ashutosh D. Wechalekar,Carol J. Whelan,Julian D. Gillmore,Philip N. Hawkins,James C. Moon +18 more
TL;DR: Native myocardial T1 mapping detects cardiac ATTR amyloid with similar diagnostic performance and disease tracking to AL amyloids, but with lower maximal T1 elevation, and appears to be an early disease marker.