Philip N. Hawkins

TL;DR: A consensus panel was convened comprising 13 specialists actively involved in the treatment of patients with amyloidosis, and a consensus was developed defining each organ involved and the criteria for response.

TL;DR: Noncontrast T1 mapping has high diagnostic accuracy for detecting cardiac AL amyloidosis, correlates well with markers of systolic and diastolic dysfunction, and is potentially more sensitive for detecting early disease than LGE imaging.

TL;DR: Substantial sub-clinical inflammation occurs widely and over prolonged periods in patients with FMF, indicating that the relatively infrequent clinically overt attacks represent the 'tip of the iceberg' in this disorder.

TL;DR: It is demonstrated that by administering the anti–human IL-1β antibody canakinumab to humans, the resulting formation of IL–1β–antibody complexes allowed the detection of in vivo–produced IL- 1β, and indicated that CAPS is entirely mediated by IL-2β and that canakinUMab treatment restores physiological IL-3β production.

TL;DR: Myocardial ECV, assessed non-invasively in the septum with equilibrium contrast cardiovascular magnetic resonance, shows gender differences in normal individuals and disease-specific variability, and shows early potential to be a useful biomarker in health and disease.