C
Catherine M. Goodman
Researcher at University of Massachusetts Amherst
Publications - 7
Citations - 1957
Catherine M. Goodman is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Colloidal gold & Peptidomimetic. The author has an hindex of 6, co-authored 7 publications receiving 1819 citations.
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Toxicity of Gold Nanoparticles Functionalized with Cationic and Anionic Side Chains
TL;DR: Concentration-dependent lysis mediated by initial electrostatic binding was observed in dye release studies using lipid vesicles, providing the probable mechanism for observed toxicity with the cationic MMPCs.
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Control of Protein Structure and Function through Surface Recognition by Tailored Nanoparticle Scaffolds
Rui Hong,Nicholas O. Fischer,Ayush Verma,Catherine M. Goodman,Todd Emrick,Vincent M. Rotello +5 more
TL;DR: Thaialkyl and thioalkylated oligo(ethylene glycol) ligands with chain-end functionality were used to fabricate water-soluble CdSe nanoparticle scaffolds, with surface recognition of chymotrypsin (ChT) achieved.
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Reversible “Irreversible” Inhibition of Chymotrypsin Using Nanoparticle Receptors
TL;DR: The conformation of the rescued chymotrypsin was characterized by fluorescence and fluorescence anisotropy, indicating that chymotin regains a high degree of native structure upon surfactant addition.
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DNA‐binding by Functionalized Gold Nanoparticles: Mechanism and Structural Requirements
TL;DR: The efficiency of DNA‐binding was determined, demonstrating in a fivefold modulation in binding a 37‐mer DNA strand, and the affinity of the nanoparticle for the DNA can be regulated by external agents, though stability of the complex is observed at relatively high ionic strengths.