C
Chiara Dalla Man
Researcher at University of Padua
Publications - 210
Citations - 12307
Chiara Dalla Man is an academic researcher from University of Padua. The author has contributed to research in topics: Insulin & Postprandial. The author has an hindex of 52, co-authored 177 publications receiving 10805 citations. Previous affiliations of Chiara Dalla Man include University of Rochester & University of Pittsburgh.
Papers
More filters
Journal ArticleDOI
Meal Simulation Model of the Glucose-Insulin System
TL;DR: A new simulation model in normal humans that describes the physiological events that occur after a meal, by employing the quantitative knowledge that has become available in recent years, is presented.
Journal ArticleDOI
In Silico Preclinical Trials: A Proof of Concept in Closed-Loop Control of Type 1 Diabetes
TL;DR: A system for in silico testing of control algorithms that has been shown to represent adequate glucose fluctuations in T1DM observed during meal challenges, and has been accepted by the Food and Drug Administration as a substitute to animal trials in the preclinical testing of closed-loop control strategies.
Journal ArticleDOI
The UVA/PADOVA Type 1 Diabetes Simulator New Features
Chiara Dalla Man,Francesco Micheletto,Dayu Lv,Marc D. Breton,Boris Kovatchev,Claudio Cobelli +5 more
TL;DR: A new version of the UVA/PADOVA Type 1 Diabetes Simulator, which was submitted to FDA in 2013, provides a more reliable framework for in silico trials, for testing glucose sensors and insulin augmented pump prediction methods, and for closed-loop single/dual hormone controller design, testing, and validation.
Journal ArticleDOI
DHEA in Elderly Women and DHEA or Testosterone in Elderly Men
K. Sreekumaran Nair,Robert A. Rizza,Peter C. O'Brien,Ketan Dhatariya,Kevin R. Short,Ajay Nehra,Janet L. Vittone,George G. Klee,Ananda Basu,Rita Basu,Claudio Cobelli,Gianna Toffolo,Chiara Dalla Man,Donald J. Tindall,L. Joseph Melton,Glenn E. Smith,Sundeep Khosla,Michael D. Jensen +17 more
TL;DR: Neither DHEA nor low-dose testosterone replacement in elderly people has physiologically relevant beneficial effects on body composition, physical performance, insulin sensitivity, or quality of life.
Journal ArticleDOI
Mechanisms of the Age-Associated Deterioration in Glucose Tolerance: Contribution of Alterations in Insulin Secretion, Action, and Clearance
Rita Basu,Elena Breda,Ann L. Oberg,Claudia C. Powell,Chiara Dalla Man,Ananda Basu,Janet L. Vittone,George G. Klee,Puneet Arora,Michael D. Jensen,Gianna Toffolo,Claudio Cobelli,Robert A. Rizza +12 more
TL;DR: It is concluded that the deterioration in glucose tolerance that occurs in healthy elderly subjects is due to a decrease in both insulin secretion and action with the severity of the defect in insulin action being explained by the degree of fatness rather than age per se.