Claire L. Gorrie

TL;DR: Tests on both synthetic and real reads show Unicycler can assemble larger contigs with fewer misassemblies than other hybrid assemblers, even when long-read depth and accuracy are low.

TL;DR: Tests on both synthetic and real reads show Unicycler can assemble larger contigs with fewer misassemblies than other hybrid assemblers, even when long read depth and accuracy are low.

TL;DR: The DNA sequence of K. pneumoniae isolates from around the world is determined and it is shown that there is a wide spectrum of diversity, including variation within shared sequences and gain and loss of whole genes, and there is an unrecognized association between the possession of specific gene profiles associated with virulence and antibiotic resistance.

TL;DR: This work advocates the use of Illumina sequencing as a first analysis step, followed by ONT reads as needed to resolve genomic structure, and demonstrates that multiplexed ONT sequencing is a valuable tool for high-throughput bacterial genome finishing.

TL;DR: Kaptive, a novel software tool that automates the process of identifying K-loci based on full locus information extracted from whole genome sequences, is introduced, highlighting the extensive diversity of Klebsiella K- loci and the proteins that they encode.