C
Craig Sturgeon
Researcher at University of Maryland, Baltimore
Publications - 14
Citations - 1382
Craig Sturgeon is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Zonulin & Intestinal permeability. The author has an hindex of 10, co-authored 14 publications receiving 1041 citations. Previous affiliations of Craig Sturgeon include Harvard University.
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Journal ArticleDOI
Natural history of celiac disease autoimmunity in a USA cohort followed since 1974
Carlo Catassi,Debby Kryszak,Bushra N. Bhatti,Craig Sturgeon,Kathy J. Helzlsouer,Sandra Clipp,Daniel Gelfond,Elaine L. Leonard Puppa,Anthony Sferruzza,Alessio Fasano +9 more
TL;DR: The CLUE study demonstrated that this increase in CD prevalence increased 2-fold in the CLUE cohort and 5-fold overall in the US since 1974 was due to an increasing number of subjects that lost the immunological tolerance to gluten in their adulthood.
Journal ArticleDOI
Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases
Craig Sturgeon,Alessio Fasano +1 more
TL;DR: This review focuses on the recent research implicating zonulin as a master regulator of intestinal permeability linked to the development of several chronic inflammatory disorders.
Journal ArticleDOI
Proof of Concept of Microbiome-Metabolome Analysis and Delayed Gluten Exposure on Celiac Disease Autoimmunity in Genetically At-Risk Infants
Maria Sellitto,Guoyun Bai,Gloria Serena,W. Florian Fricke,Craig Sturgeon,Pawel Gajer,James R. White,Sara S. K. Koenig,Joyce M. Sakamoto,Dustin Boothe,Rachel E. Gicquelais,Deborah Kryszak,Elaine L. Leonard Puppa,Carlo Catassi,Carlo Catassi,Jacques Ravel,Alessio Fasano +16 more
TL;DR: It is shown that infants genetically susceptible to CD who are exposed to gluten early mount an immune response against gluten and develop CD autoimmunity more frequently than at-risk infants in which gluten exposure is delayed until 12 months of age.
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Biomarkers of Environmental Enteropathy, Inflammation, Stunting, and Impaired Growth in Children in Northeast Brazil.
Richard L. Guerrant,Álvaro M. Leite,Relana Pinkerton,Pedro H. Q. S. Medeiros,Paloma A. Cavalcante,Mark D. DeBoer,Margaret Kosek,Christopher Duggan,Andrew T. Gewirtz,Jonathan C. Kagan,Anna E. Gauthier,Jonathan R. Swann,Jordi Mayneris-Perxachs,David T. Bolick,Elizabeth A. Maier,Marjorie M. Guedes,Sean R. Moore,William A. Petri,Alexandre Havt,Ila F. N. Lima,Mara M. G. Prata,Josyf C. Michaleckyj,Rebecca J. Scharf,Craig Sturgeon,Alessio Fasano,Aldo A. M. Lima +25 more
TL;DR: Key noninvasive biomarkers of intestinal barrier disruption, LPS translocation and of intestinal and systemic inflammation can help elucidate how to recognize, understand, and assess effective interventions for enteropathy and its growth and developmental consequences in children in impoverished settings.
Journal ArticleDOI
Differential immune responses and microbiota profiles in children with autism spectrum disorders and co-morbid gastrointestinal symptoms.
Destanie R. Rose,Houa Yang,Gloria Serena,Craig Sturgeon,Bing Ma,Milo Careaga,Heather K. Hughes,Kathy Angkustsiri,Melissa Rose,Irva Hertz-Picciotto,Judy Van de Water,Robin L Hansen,Jacques Ravel,Alessio Fasano,Paul Ashwood +14 more
TL;DR: It is suggested that children with ASD who experience GI symptoms have an imbalance in their immune response, possibly influenced by or influencing metagenomic changes, and may have a propensity to impaired gut barrier function which may contribute to their symptoms and clinical outcome.