D
David Della-Morte
Researcher at University of Rome Tor Vergata
Publications - 186
Citations - 6979
David Della-Morte is an academic researcher from University of Rome Tor Vergata. The author has contributed to research in topics: Internal medicine & Population. The author has an hindex of 33, co-authored 169 publications receiving 4941 citations. Previous affiliations of David Della-Morte include Columbia University & Open University.
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Journal ArticleDOI
Oxidative stress, aging, and diseases.
Ilaria Liguori,Gennaro Russo,Francesco Curcio,Giulia Bulli,Luisa Aran,David Della-Morte,Gaetano Gargiulo,Gianluca Testa,Gianluca Testa,Francesco Cacciatore,Domenico Bonaduce,Pasquale Abete +11 more
TL;DR: Given the important role of oxidative stress in the pathogenesis of many clinical conditions and aging, antioxidant therapy could positively affect the natural history of several diseases, but further investigation is needed to evaluate the real efficacy of these therapeutic interventions.
Journal ArticleDOI
Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1-uncoupling protein 2 pathway.
David Della-Morte,Kunjan R. Dave,Richard A. DeFazio,Y. C. Bao,Ami P. Raval,Miguel A. Perez-Pinzon +5 more
TL;DR: In vivo resveratrol pretreatment confers neuroprotection similar to IPC via the SIRT1-UCP2 pathway, and significantly increased the ADP/O ratio in hippocampal mitochondria reflecting enhanced ATP synthesis efficiency.
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Sarcopenia: assessment of disease burden and strategies to improve outcomes.
Ilaria Liguori,Gennaro Russo,Luisa Aran,Giulia Bulli,Francesco Curcio,David Della-Morte,Gaetano Gargiulo,Gianluca Testa,Gianluca Testa,Francesco Cacciatore,Domenico Bonaduce,Pasquale Abete +11 more
TL;DR: Because sarcopenia is associated with important adverse health outcomes, such as frailty, hospitalization, and mortality, several therapeutic strategies have been identified that involve exercise training, nutritional supplementation, hormonal therapies, and novel strategies and are still under investigation.
Journal ArticleDOI
Obesity and colorectal cancer: Role of adipokines in tumor initiation and progression
Silvia Riondino,Mario Roselli,Raffaele Palmirotta,David Della-Morte,Patrizia Ferroni,Fiorella Guadagni +5 more
TL;DR: The hypothesis is that an unfavorable adipokine profile, with a reduction of those with an anti-inflammatory and anti-cancerous activity, might serve as a prognostic factor in CRC patients and that adipokines or their analogues/antagonists might become useful agents in the management or chemoprevention of CRC.
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Cognitive impairment and cardiovascular diseases in the elderly. A heart-brain continuum hypothesis
Pasquale Abete,David Della-Morte,Gaetano Gargiulo,Claudia Basile,Assunta Langellotto,Gianluigi Galizia,Gianluca Testa,V. Canonico,Domenico Bonaduce,Francesco Cacciatore +9 more
TL;DR: A continuum among hypertension, coronary artery disease, atrial fibrillation and chronic heart failure with to the development of cognitive impairment and progression to dementia has been hypothesized.