D
David K. Smith
Researcher at University of Hong Kong
Publications - 70
Citations - 6136
David K. Smith is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Influenza A virus & Influenza A virus subtype H5N1. The author has an hindex of 27, co-authored 68 publications receiving 4564 citations. Previous affiliations of David K. Smith include Li Ka Shing Faculty of Medicine, University of Hong Kong & Shantou University.
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ggtree: an R package for visualization and annotation of phylogenetic trees with their covariates and other associated data
TL;DR: An r package, ggtree, which provides programmable visualization and annotation of phylogenetic trees, which can read more tree file formats than other softwares, and support visualization of phylo, multiphylo, phylo4, phyla4d, obkdata and phyloseq tree objects defined in other r packages.
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The genesis and source of the H7N9 influenza viruses causing human infections in China
Tommy Tsan-Yuk Lam,Jia Wang,Jia Wang,Yongyi Shen,Yongyi Shen,Yongyi Shen,Boping Zhou,Lian Duan,CL Cheung,Chi Ma,Chi Ma,Samantha Lycett,Connie Y. H. Leung,Xinchun Chen,Lifeng Li,Lifeng Li,Wenshan Hong,Yujuan Chai,Linlin Zhou,Huyi Liang,Huyi Liang,Zhihua Ou,Zhihua Ou,Yongmei Liu,Yongmei Liu,Amber Farooqui,David J. Kelvin,Leo L.M. Poon,David K. Smith,David K. Smith,Oliver G. Pybus,Gabriel M. Leung,Gabriel M. Leung,Yuelong Shu,Robert G. Webster,Richard J. Webby,Joseph S. M. Peiris,Andrew Rambaut,Andrew Rambaut,Hongbo Zhu,Hongbo Zhu,Yi Guan,Yi Guan +42 more
TL;DR: It is shown that H7 viruses probably transferred from domestic duck to chicken populations in China on at least two independent occasions and subsequently reassorted with enzootic H9N2 viruses to generate the H7N9 outbreak lineage, and a related previously unrecognized H7n7 lineage.
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Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia
Jamal S. M. Sabir,Tommy Tsan-Yuk Lam,Mohamed M. Ahmed,Lifeng Li,Yongyi Shen,Salah E. M. Abo-Aba,Muhammad I. Qureshi,Mohamed Abu-Zeid,Yu Zhang,Mohammad A. Khiyami,Njud S. Alharbi,Nahid H. Hajrah,Meshaal J. Sabir,Mohammed H. Z. Mutwakil,Saleh A. Kabli,Faten A. S. Alsulaimany,Abdullah Y. Obaid,Boping Zhou,David K. Smith,Edward C. Holmes,Hongbo Zhu,Yi Guan +21 more
TL;DR: Camels serve as an important reservoir for the maintenance and diversification of the MERS-CoVs and are the source of human infections with this virus, according to surveillance in Saudi Arabia in 2014 and 2015.
Journal ArticleDOI
Protein flexibility and intrinsic disorder.
Predrag Radivojac,Zoran Obradovic,David K. Smith,Guang Zhu,Slobodan Vucetic,Celeste J. Brown,J. David Lawson,A. Keith Dunker +7 more
TL;DR: The distinctive amino acid biases of high‐B‐factor ordered regions, short disordered regions, and long dis ordered regions indicate that the sequence determinants for these flexibility categories differ from one another, whereas the significantly‐greater‐than‐chance predictability of these categories from sequence suggest that flexible ordered regions and short disorder are, to a significant degree, encoded at the primary structure level.
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Codon usage bias and the evolution of influenza A viruses. Codon Usage Biases of Influenza Virus.
TL;DR: It was found that the 1918 pandemic H1N1 virus contained genes with mammalian-like viral codon usage patterns, indicating that the introduction of this virus to humans was not through in toto transfer of an avian influenza virus.