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Denise Hilfiker-Kleiner
Researcher at Hannover Medical School
Publications - 234
Citations - 18370
Denise Hilfiker-Kleiner is an academic researcher from Hannover Medical School. The author has contributed to research in topics: Peripartum cardiomyopathy & Heart failure. The author has an hindex of 64, co-authored 221 publications receiving 15815 citations. Previous affiliations of Denise Hilfiker-Kleiner include Intermountain Medical Center & Hochschule Hannover.
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Journal ArticleDOI
ESC Guidelines on the management of cardiovascular diseases during pregnancy: the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC).
Vera Regitz-Zagrosek,Carina Blomström Lundqvist,Claudio Borghi,Renata Cifkova,Rafael Ferreira,Jean-Michel Foidart,J Simon R Gibbs,Christa Gohlke-Baerwolf,Bulent Gorenek,Bernard Iung,Mike Kirby,Angela H E M Maas,João Morais,Petros Nihoyannopoulos,Petronella G. Pieper,Patrizia Presbitero,Jolien W. Roos-Hesselink,Maria Schaufelberger,Ute Seeland,Lucia Torracca,Jeroen J. Bax,A Auricchio,Helmut Baumgartner,Claudio Ceconi,Veronica Dean,Christi Deaton,Robert Fagard,Christian Funck-Brentano,David Hasdai,Arno W. Hoes,Juhani Knuuti,Philippe Kolh,Theresa McDonagh,Cyril Moulin,Don Poldermans,Bogdan Alexandru Popescu,Zeljko Reiner,Udo Sechtem,Per Anton Sirnes,Adam Torbicki,Alec Vahanian,Stephan Windecker,Carlos Aguiar,Nawwar Al-Attar,Angeles Alonso Garcia,Anna Antoniou,I M Coman,Uri Elkayam,Miguel Ángel Gómez-Sánchez,Nina Gotcheva,Denise Hilfiker-Kleiner,Róbert Gábor Kiss,Anastasia Kitsiou,Karen T S Konings,Gregory Y.H. Lip,Athanasios J. Manolis,Alexandre Mebaaza,Iveta Mintale,Marie Claude Morice,Barbara J.M. Mulder,Agnes Pasquet,Susanna Price,Silvia G. Priori,Maria J Salvador,Avraham Shotan,Candice K. Silversides,Sven O Skouby,Jörg Ingolf Stein,Pilar Tornos,Niels Vejlstrup,Fiona Walker,Carole A. Warnes +71 more
TL;DR: Recommendations for the prevention and management of venous thrombo-embolism in pregnancy and puerperium and the associated risk groups according to risk factors: definition and preventive measures are presented.
Journal ArticleDOI
Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy
Karen Sliwa,Denise Hilfiker-Kleiner,Mark C. Petrie,Alexandre Mebazaa,Burkert Pieske,Eckhart Buchmann,Vera Regitz-Zagrosek,Maria Schaufelberger,Luigi Tavazzi,Dirk J. van Veldhuisen,Hugh Watkins,Ajay J. Shah,Petar M. Seferović,Uri Elkayam,Sabine Pankuweit,Zoltán Papp,Frédéric Mouquet,John J.V. McMurray +17 more
TL;DR: The present position statement offers a state‐of‐the‐art summary of what is known about risk factors for potential pathophysiological mechanisms, clinical presentation of, and diagnosis and management of PPCM.
Journal ArticleDOI
A Cathepsin D-Cleaved 16 kDa Form of Prolactin Mediates Postpartum Cardiomyopathy
Denise Hilfiker-Kleiner,Karol Kamiński,Edith Podewski,Tomasz A. Bonda,Arnd Schaefer,Karen Sliwa,Olaf Forster,Anja Quint,Ulf Landmesser,Carola Doerries,Maren Luchtefeld,Valeria Poli,Michael D. Schneider,Jean-Luc Balligand,Fanny Desjardins,Aftab A. Ansari,Ingrid Struman,Ngoc Quynh Nhu Nguyen,Nils H. Zschemisch,Gunnar Klein,Gerd Heusch,Rainer Schulz,Andres Hilfiker,Helmut Drexler +23 more
TL;DR: It is shown that female mice with a cardiomyocyte-specific deletion of stat3 develop PPCM, implying that inhibition of prolactin release may represent a novel therapeutic strategy for P PCM.
Journal ArticleDOI
Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instability.
Bernhard Schieffer,Elisabeth Schieffer,Denise Hilfiker-Kleiner,Andres Hilfiker,Petri T. Kovanen,Maija Kaartinen,Jörg Nussberger,Wolfgang Harringer,Helmut Drexler +8 more
TL;DR: The observation that Ang II induces IL-6 and their colocalization with the AT(1) receptor and ACE is consistent with the notion that the RAS may contribute to inflammatory processes within the vascular wall and to the development of acute coronary syndromes.
Journal ArticleDOI
Statin-Induced Improvement of Endothelial Progenitor Cell Mobilization, Myocardial Neovascularization, Left Ventricular Function, and Survival After Experimental Myocardial Infarction Requires Endothelial Nitric Oxide Synthase
Ulf Landmesser,Niels Engberding,Ferdinand H. Bahlmann,Arnd Schaefer,Antje Wiencke,Andre Heineke,Stephan Spiekermann,Denise Hilfiker-Kleiner,Christian Templin,Daniel Kotlarz,Maja Mueller,Martin Fuchs,Burkhard Hornig,Hermann Haller,Helmut Drexler +14 more
TL;DR: It is suggested that increased eNO availability is required for statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, LV dysfunction, interstitial fibrosis, and survival after MI.