Dhanya Haridas

TL;DR: A further understanding of the system is required to develop an effective anticancer regimen and a combination therapy that comprises an anti-EGFR and a chemotherapeutic/chemopreventive agent will exhibit a multi-pronged approach that can be developed into a highly attractive and specific molecular oriented remedy.

TL;DR: The results suggest that MUC16 has a dual role in breast cancer cell proliferation by interacting with JAK2 and by inhibiting the apoptotic process through downregulation of TRAIL.

TL;DR: Analysis of the expression of MUC16 during the initiation, progression and metastasis of pancreatic cancer and identified PC cell lines that express M UC16, which can be used in future studies to elucidate its functional role in PC.

TL;DR: Mulins are emerging as attractive targets for developing novel therapeutic approaches for lung cancer, and several strategies targeting mucin expression and function are currently being investigated to control lung cancer progression.

TL;DR: In this review, the various aspects of MUC16 are discussed, which include its discovery, structure, and biological significance both in benign and malignant conditions with an attempt to dissect its functional relevance.