D
Dominic Job
Researcher at University of Edinburgh
Publications - 76
Citations - 5205
Dominic Job is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Schizophrenia & Grey matter. The author has an hindex of 35, co-authored 75 publications receiving 5003 citations. Previous affiliations of Dominic Job include University of Dundee & Edinburgh Napier University.
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Principles in the Evolutionary Design of Digital Circuits—Part II
TL;DR: It is argued that by studying evolved designs of gradually increasing scale, one might be able to discern new, efficient, and generalisable principles of design, which explain how to build systems which are too large to evolve.
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Structural disconnectivity in schizophrenia: a diffusion tensor magnetic resonance imaging study.
J. Burns,Dominic Job,Mark E. Bastin,Heather C. Whalley,Tom MacGillivray,Eve C. Johnstone,Stephen M. Lawrie +6 more
TL;DR: The findings of reduced white matter tract integrity in the left uncinate fasciculus and left arcuate fascicule suggest that there is frontotemporal and frontoparietal structural disconnectivity in schizophrenia.
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Grey matter changes over time in high risk subjects developing schizophrenia
TL;DR: VBM was used to map changes in Grey Matter Density in 65 young adults at high risk of schizophrenia, for familial reasons, and 19 healthy young adults, over a period of approximately 2 years, and showed a different spatial pattern of reductions in GMD than those who did not in within group comparisons.
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White matter abnormalities in bipolar disorder and schizophrenia detected using diffusion tensor magnetic resonance imaging
Jessika E. Sussmann,G. Katherine S. Lymer,James McKirdy,T. William J. Moorhead,Susana Muñoz Maniega,Dominic Job,Jeremy Hall,Mark E. Bastin,Eve C. Johnstone,Stephen M. Lawrie,Andrew M. McIntosh +10 more
TL;DR: Diffusion tensor imaging studies suggest altered connectivity in both schizophrenia and bipolar disorder, and results imply an overlap in white matter pathology, possibly relating to risk factors common to both disorders.
Journal ArticleDOI
Structural gray matter differences between first-episode schizophrenics and normal controls using voxel-based morphometry.
Dominic Job,Heather C. Whalley,Sarah McConnell,Mike Glabus,Eve C. Johnstone,Stephen M. Lawrie +5 more
TL;DR: Comparison of gray matter segments from T1 structural MR images of the brain in first-episode schizophrenic subjects and normal control subjects using automated voxel-based morphometry (VBM) identified significant decreases in gray matter in schizophrenics relative to the normal control group.