D
Drazen M. Jukic
Researcher at University of South Florida
Publications - 77
Citations - 2957
Drazen M. Jukic is an academic researcher from University of South Florida. The author has contributed to research in topics: Melanoma & Cancer. The author has an hindex of 26, co-authored 77 publications receiving 2634 citations. Previous affiliations of Drazen M. Jukic include University of Pittsburgh & Veterans Health Administration.
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Journal ArticleDOI
OpenSlide: A vendor-neutral software foundation for digital pathology
TL;DR: The design and implementation of OpenSlide is presented, a vendor-neutral C library for reading and manipulating digital slides of diverse vendor formats that is extensible and easily interfaced to various programming languages.
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Neoadjuvant Treatment of Regional Stage IIIB Melanoma With High-Dose Interferon Alfa-2b Induces Objective Tumor Regression in Association With Modulation of Tumor Infiltrating Host Cellular Immune Responses
Stergios J. Moschos,Howard Edington,Stephanie R. Land,Uma N. M. Rao,Drazen M. Jukic,Janice Shipe-Spotloe,John M. Kirkwood +6 more
TL;DR: Neoadjuvant HDI is highly effective for the treatment of palpable stage IIIB-C melanoma, and the findings of this study implicate an indirect immunomodulatory mechanism rather than a direct antitumor mechanism.
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Use of whole slide imaging in surgical pathology quality assurance: design and pilot validation studies.
TL;DR: A retrospective comparative study in which 24 full genitourinary cases were independently reviewed with traditional microscopy and whole slide digital images, it is agreed that automated WSI is a viable potential modality for surgical pathology QA, especially in multifacility health systems that would like to establish interfacility QA.
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Primary histologic diagnosis using automated whole slide imaging: a validation study
TL;DR: The results indicated that the image information contained in current whole slide images is sufficient for pathologists to make reliable diagnostic decisions and compose complex diagnostic reports, but this does not mean that WSI is as good as a microscope.
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Modulation of Signal Transducers and Activators of Transcription 1 and 3 Signaling in Melanoma by High-Dose IFNα2b
Wenjun Wang,Howard Edington,Uma N. M. Rao,Drazen M. Jukic,Stephanie R. Land,Soldano Ferrone,John M. Kirkwood +6 more
TL;DR: IFNα2b significantly modulates the balance of STAT1/STAT3 in tumor cells and host lymphocytes, leading to up-regulation of TAP2 and augmented host antitumor response.