F
Fenna M. Krienen
Researcher at Harvard University
Publications - 33
Citations - 14588
Fenna M. Krienen is an academic researcher from Harvard University. The author has contributed to research in topics: Prefrontal cortex & Neocortex. The author has an hindex of 18, co-authored 27 publications receiving 11824 citations. Previous affiliations of Fenna M. Krienen include George Washington University & Broad Institute.
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Journal ArticleDOI
The organization of the human cerebral cortex estimated by intrinsic functional connectivity
B.T. Thomas Yeo,Fenna M. Krienen,Jorge Sepulcre,Jorge Sepulcre,Mert R. Sabuncu,Mert R. Sabuncu,Danial Lashkari,Marisa O. Hollinshead,Marisa O. Hollinshead,Joshua L. Roffman,Jordan W. Smoller,Lilla Zöllei,Jonathan R. Polimeni,Bruce Fischl,Bruce Fischl,Hesheng Liu,Randy L. Buckner +16 more
TL;DR: In this paper, the organization of networks in the human cerebrum was explored using resting-state functional connectivity MRI data from 1,000 subjects and a clustering approach was employed to identify and replicate networks of functionally coupled regions across the cerebral cortex.
Journal ArticleDOI
Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease
Randy L. Buckner,Jorge Sepulcre,Tanveer Talukdar,Fenna M. Krienen,Hesheng Liu,Trey Hedden,Jessica R. Andrews-Hanna,Reisa A. Sperling,Keith A. Johnson +8 more
TL;DR: To identify regions of high connectivity in the human cerebral cortex, a computationally efficient approach was applied to map the degree of intrinsic functional connectivity across the brain and explored whether the topography of hubs could explain the pattern of vulnerability in Alzheimer's disease (AD).
Journal ArticleDOI
Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain.
Arpiar Saunders,Arpiar Saunders,Evan Z. Macosko,Evan Z. Macosko,Alec Wysoker,Alec Wysoker,Melissa Goldman,Melissa Goldman,Fenna M. Krienen,Fenna M. Krienen,Heather de Rivera,Heather de Rivera,Elizabeth Bien,Elizabeth Bien,Matthew A. Baum,Matthew A. Baum,Laura Bortolin,Laura Bortolin,Shuyu Wang,Aleksandrina Goeva,James Nemesh,James Nemesh,Nolan Kamitaki,Nolan Kamitaki,Sara A. Brumbaugh,Sara A. Brumbaugh,David Kulp,David Kulp,Steven A. McCarroll,Steven A. McCarroll +29 more
TL;DR: Features of brain organization are revealed, including a gene-expression module for synthesizing axonal and presynaptic components, patterns in the co-deployment of voltage-gated ion channels, functional distinctions among the cells of the vasculature and specialization of glutamatergic neurons across cortical regions.
Journal ArticleDOI
Opportunities and limitations of intrinsic functional connectivity MRI
TL;DR: The potential of fcMRI is discussed in the context of its limitations, suggesting that it is constrained by, but not fully dictated by, anatomic connectivity.
Journal ArticleDOI
Segregated Fronto-Cerebellar Circuits Revealed by Intrinsic Functional Connectivity
TL;DR: The presence of circuits that involve prefrontal regions confirms that the cerebellum participates in networks important to cognition including a specific fronto-cerebellar circuit that interacts with the default network.