F
Francesco Basile
Researcher at University of Catania
Publications - 158
Citations - 3423
Francesco Basile is an academic researcher from University of Catania. The author has contributed to research in topics: Hernia & Laparoscopic surgery. The author has an hindex of 29, co-authored 151 publications receiving 2868 citations.
Papers
More filters
Journal ArticleDOI
Potential role of probiotics on colorectal cancer prevention
Mario Uccello,Giulia Malaguarnera,Francesco Basile,Velia D'Agata,Michele Malaguarnera,Gaetano Bertino,Marco Vacante,Filippo Drago,Antonio Biondi +8 more
TL;DR: Several mechanisms could explain the preventive action of probiotics against colorectal cancer onset: alteration of the intestinal microflora; inactivation of cancerogenic compounds; competition with putrefactive and pathogenic microbiota; improvement of the host’s immune response; and inhibition of tyrosine kinase signaling pathways.
Journal ArticleDOI
PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches.
Giovanni Ligresti,Loredana Militello,Linda S. Steelman,Andrea Cavallaro,Francesco Basile,Ferdinando Nicoletti,Franca Stivala,James A. McCubrey,Massimo Libra +8 more
TL;DR: Analyses of PIK3CA mutations reveals that they increase the PI3K signal, stimulate downstream Akt signaling, promote growth factor-independent growth and increase cell invasion and metastasis.
Journal ArticleDOI
Mediterranean diet and cardiovascular risk factors: a systematic review.
Giuseppe Grosso,Antonio Mistretta,Alessandro Frigiola,Salvatore Gruttadauria,Antonio Biondi,Francesco Basile,Paola Vitaglione,Nicolantonio D'Orazio,Fabio Galvano +8 more
TL;DR: Most of the studies showed favorable effects of MD on CVD, although a certain degree of controversy remains in the respect of some issues, as obesity.
Journal ArticleDOI
LncRNA UCA1, Upregulated in CRC Biopsies and Downregulated in Serum Exosomes, Controls mRNA Expression by RNA-RNA Interactions.
Cristina Barbagallo,Duilia Brex,Angela Caponnetto,Matilde Cirnigliaro,Marina Scalia,Antonio Magnano,Rosario Caltabiano,Davide Barbagallo,Antonio Biondi,Alessandro Cappellani,Francesco Basile,Cinzia Di Pietro,Michele Purrello,Marco Ragusa +13 more
TL;DR: The UCA1 regulatory axis would represent a promising target to develop innovative RNA-based therapeutics against CRC and functional enrichment analysis of the RNA-RNA network controlled by U CA1 suggested its potential involvement in cellular migration.
Journal ArticleDOI
Health related quality of life in colorectal cancer patients: state of the art.
Stefano Marventano,Maria João Forjaz,Giuseppe Grosso,Antonio Mistretta,Gabriele Giorgianni,Alessio Platania,Gangi S,Francesco Basile,Antonio Biondi +8 more
TL;DR: Despite that CRC patients have a relatively good quality of life compared with the general population, a wide range of intervention could be undertaken to improve their QoL.