Frédérick Barreau

TL;DR: The gut-associated lymphoid tissue (GALT) consists of isolated or aggregated lymphoid follicles forming Peyer's patches (PPs), which can be considered as the immune sensors of the intestine by their ability to transport luminal antigens and bacteria.

TL;DR: In vivo and ex vivo data prove that TiO2-NPs would possibly translocate through both the regular epithelium lining the ileum and through Peyer’s patches, would induce epithelia impairment, and would persist in gut cells where they would possibly induce chronic damage.

TL;DR: A role for early psychological factors in the regulation of colonic mucosal barrier in later life is suggested, as judged by enhanced MPO colonic levels, total gut permeability, and macroscopic lesions.

TL;DR: It is indicated that NGF triggers and maintains long-term alterations of visceral sensitivity and gut mucosal integrity induced by MD, and anti-NGF antibodies abolished these effects.

TL;DR: A review of the literature on the influence of early traumatic experiences on the development of Irritable Bowel Syndrome (IBS) can be found in this paper, where different neonatal stress models, such as neonatal maternal deprivation (NMD), neonatal colonic irritation (inflammatory stim- uli), and neonatal colic pain (rectal distension) have been described to mimic some cardinal features of IBS.