G
Gabriela Rondon
Researcher at University of Texas MD Anderson Cancer Center
Publications - 307
Citations - 10640
Gabriela Rondon is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 43, co-authored 277 publications receiving 9089 citations. Previous affiliations of Gabriela Rondon include University of Texas at Austin.
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Journal ArticleDOI
Engraftment of Allogeneic Hematopoietic Progenitor Cells With Purine Analog-Containing Chemotherapy: Harnessing Graft-Versus-Leukemia Without Myeloablative Therapy
Sergio Giralt,Elihu H. Estey,Maher Albitar,Koen van Besien,Gabriela Rondon,Paolo Anderlini,Susan O'Brien,Issa F. Khouri,James Gajewski,Rakesh Mehra,David F. Claxton,Borje S. Andersson,Miloslav Beran,Donna Przepiorka,Charles Koller,Steve Kornblau,Martin Korbling,Michael J. Keating,Hagop M. Kantarjian,Richard E. Champlin +19 more
TL;DR: It is concluded that purine analog-containing nonmyeloablative regimens allow engraftment of HLA-compatible hematopoietic progenitor cells and warrants further study in patients with leukemia who are ineligible for conventional transplantation with myeloablatives either because of age or concurrent medical conditions.
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Hepatocytes and epithelial cells of donor origin in recipients of peripheral-blood stem cells.
Martin Korbling,Ruth L. Katz,Abha Khanna,Arnout C.C. Ruifrok,Gabriela Rondon,Maher Albitar,Richard E. Champlin,Zeev Estrov +7 more
TL;DR: All six recipients of sex-mismatched transplants showed evidence of complete hematopoietic donor chimerism and the presence of donor cells in the biopsy specimens did not seem to depend on the intensity of tissue damage induced by graft-versus-host disease.
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Cord-blood engraftment with ex vivo mesenchymal-cell coculture.
Marcos de Lima,Ian McNiece,Simon N. Robinson,Mark F. Munsell,Mary Eapen,Mary M. Horowitz,Amin M. Alousi,Rima M. Saliba,John McMannis,Indreshpal Kaur,Partow Kebriaei,Simrit Parmar,Uday R. Popat,Chitra Hosing,Richard E. Champlin,Catherine M. Bollard,Jeffrey J. Molldrem,Roy B. Jones,Yago Nieto,Borje S. Andersson,Nina Shah,Betul Oran,Laurence J.N. Cooper,Laura L. Worth,Muzaffar H. Qazilbash,Martin Korbling,Gabriela Rondon,Stefan O. Ciurea,Doyle Bosque,I. Maewal,Paul J. Simmons,Elizabeth J. Shpall +31 more
TL;DR: Transplantation of cord-blood cells expanded ex vivo in cocultures with allogeneic mesenchymal stromal cells appeared to be safe and effective and significantly improved engraftment, as compared with unmanipulated cord blood only.
Journal ArticleDOI
Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells
Partow Kebriaei,Harjeet Singh,M. Helen Huls,Matthew J. Figliola,Roland L. Bassett,Simon Olivares,Bipulendu Jena,Margaret J. Dawson,Pappanaicken R. Kumaresan,Shihuang Su,Sourindra Maiti,Jianliang Dai,Branden S. Moriarity,Marie Andrée Forget,Vladimir Senyukov,Aaron F. Orozco,Tingting Liu,Jessica McCarty,Rineka Jackson,Judy S. Moyes,Gabriela Rondon,Muzaffar H. Qazilbash,Stefan O. Ciurea,Amin M. Alousi,Yago Nieto,Katy Rezvani,David Marin,Uday R. Popat,Chitra Hosing,Elizabeth J. Shpall,Hagop M. Kantarjian,Michael J. Keating,William G. Wierda,Kim Anh Do,David A. Largaespada,Dean A. Lee,Dean A. Lee,Perry B. Hackett,Richard E. Champlin,Laurence J.N. Cooper,Laurence J.N. Cooper +40 more
TL;DR: CD19-specific CAR T cells generated with Sleeping Beauty transposon/transposase platforms were safe, and may provide additional cancer control as planned infusions after HSCT, and support further clinical development of this nonviral gene therapy approach.
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CD8-depleted donor lymphocyte infusion as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation
Sergio Giralt,Jeane P. Hester,Yang O. Huh,Cheryl F Hirsch-Ginsberg,Gabriela Rondon,D. Seong,M. S. Lee,James Gajewski,K. Van Besien,Issa F. Khouri,Rakesh Mehra,Donna Przepiorka,Martin Korbling,Moshe Talpaz,Hagop M. Kantarjian,H. Fischer,Albert B. Deisseroth,Richard E. Champlin +17 more
TL;DR: It is concluded that donor lymphocyte infusions depleted of CD8-depleted donor peripheral blood lymphocytes can induce remissions with a low rate of severe acute GVHD in patients with CML who relapse after allogeneic BMT, supporting the hypothesis that CD8+ lymphocytes are important effectors of GV HD, but may not be essential for the graft-versus-leukemia effect against this disease.