G
George Notas
Researcher at University of Crete
Publications - 116
Citations - 3645
George Notas is an academic researcher from University of Crete. The author has contributed to research in topics: Receptor & Somatostatin. The author has an hindex of 28, co-authored 109 publications receiving 3208 citations. Previous affiliations of George Notas include Foundation for Research & Technology – Hellas & University of California, San Diego.
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Journal ArticleDOI
Antiproliferative and apoptotic effects of selective phenolic acids on T47D human breast cancer cells: potential mechanisms of action.
Marilena Kampa,Vassilia-Ismini Alexaki,George Notas,Artemissia-Phoebe Nifli,Anastassia Nistikaki,Anastassia Hatzoglou,Efstathia Bakogeorgou,Elena Kouimtzoglou,George Blekas,Dimitrios Boskou,Achille Gravanis,Elias Castanas +11 more
TL;DR: Phenolic acids exert a direct antiproliferative action, evident at low concentrations, comparable with those found in biological fluids after ingestion of foods rich in phenolic acids.
Journal ArticleDOI
Potent inhibitory action of red wine polyphenols on human breast cancer cells.
Athina Damianaki,Efstathia Bakogeorgou,M. Kampa,George Notas,Anastassia Hatzoglou,Simone Panagiotou,Claudia Gemetzi,Elias A. Kouroumalis,Pierre-Marie Martin,Elias Castanas +9 more
TL;DR: The results suggest that low concentrations of polyphenols, and consecutively, consumption of wine, or other polyphenol‐rich foods and beverages, could have a beneficial antiproliferative effect on breast cancer cell growth.
Journal ArticleDOI
Wine antioxidant polyphenols inhibit the proliferation of human prostate cancer cell lines.
M. Kampa,Anastassia Hatzoglou,George Notas,Athina Damianaki,Efstathia Bakogeorgou,Claudia Gemetzi,Elias A. Kouroumalis,Pierre-Marie Martin,Elias Castanas +8 more
TL;DR: A direct inhibitory effect of low concentrations of antioxidant wine phenols on the proliferation of human prostate cancer cell lines mediated by the production of NO is shown, further suggesting potential beneficial effects of wine and other phenol-containing foods or drinks for the control of prostate cancercell growth.
Book ChapterDOI
Polyphenols and cancer cell growth
TL;DR: The effects of polyphenols on cancer cell fate, leading towards growth, differentiation and apoptosis are reviewed, and clues about their possible pharmaceutical exploitation in the field of oncology are provided.
Journal ArticleDOI
A new automated method for the determination of the Total Antioxidant Capacity (TAC) of human plasma, based on the crocin bleaching assay
Marilena Kampa,Anastasia Nistikaki,Vassilios Tsaousis,Niki Maliaraki,George Notas,Elias Castanas +5 more
TL;DR: An automated assay to calculate the antioxidant capacity of plasma after a subtraction of all interference deriving from endogenous and/or exogenous metabolites is presented, which can be used as a useful indicator of the antioxidant value of foods and beverages in the daily diet.