George S. Jackson

TL;DR: This review offers an introduction to the principles and generic applications of FT-ICR mass spectrometry, directed to readers with no prior experience with the technique, and lists accurate fundamental constants needed for ultrahigh-precision analysis.

TL;DR: The effect of salt concentration on analyte response using electrospray ionization mass spectrometry (ESI-MS) was measured and compared to that predicted by Enke’s equilibrium partitioning model, which shows an increase in the Analyte response factor with increasing electrolyte concentration.

TL;DR: The effect of gas-phase proton transfer reactions on the mass spectral response of solvents and analytes with known gas- phase proton affinities was evaluated and the analyte response was suppressed or eliminated insolvents with gas- Phase Proton affinity higher than that of the analytes.

TL;DR: Critical questions about the absorption and tissue uptake of complex polyphenols such as the proanthocyanins can be answered by labeling thesepolyphenols with (14)C-sucrose in plant cell culture and then purifying them for use in animal experiments, routinely carried out with great sensitivity, specificity and quantification by LC-tandem mass spectrometry.

TL;DR: Observations indicate that some grape-derived polyphenolics do reach the brain, which suggests their potential value for applications in neurodegenerative disorders.