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Guy Smagghe

Researcher at Ghent University

Publications -  813
Citations -  32578

Guy Smagghe is an academic researcher from Ghent University. The author has contributed to research in topics: Biology & RNA interference. The author has an hindex of 69, co-authored 755 publications receiving 26578 citations. Previous affiliations of Guy Smagghe include Vrije Universiteit Brussel & Southwest University.

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RNAi-based gene silencing through dsRNA injection or ingestion against the African sweet potato weevil Cylas puncticollis (Coleoptera: Brentidae).

TL;DR: It is concluded that the full potential of RNAi in SPW is affected by the presence of nucleases, so it is necessary constantly to provide new dsRNA and/or protect it against possible degradation in order to obtain a higher RNAi efficacy.
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Carbohydrate-binding activity of the type-2 ribosome-inactivating protein SNA-I from elderberry (Sambucus nigra) is a determining factor for its insecticidal activity.

TL;DR: An artificial diet supplemented with different concentrations of the purified RIP reduced survival and fecundity of pea aphids Acyrthosiphon pisum and feeding of tobacco aphids, Myzus nicotianae, resulted in a delayed development and reduced adult survival and also the fertility parameters of the surviving aphids were reduced, suggesting that a population of aphids would build up significantly slower on plants expressing SNA-I.
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Effect of oral infection with Kashmir bee virus and Israeli acute paralysis virus on bumblebee (Bombus terrestris) reproductive success

TL;DR: Israeli acute paralysis virus together with Acute bee paralysis virus (ABPV) and Kashmir bee virus (KBV) constitute a complex of closely related dicistroviruses and it is vital to understand how viral prevalence can affect wild bee populations because disturbance of the natural host-virus association may deteriorate the already critically endangered status of many bumblebee species.
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Significance of penetration, excretion, and transovarial uptake to toxicity of three insect growth regulators in predatory lacewing adults

TL;DR: The current data indicate the importance of penetration through the insect cuticle, however, other mechanisms are likely to be involved in the selectivity of the current IGRs towards this beneficial insect.
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Expression of Sambucus nigra agglutinin (SNA-I′) from elderberry bark in transgenic tobacco plants results in enhanced resistance to different insect species

TL;DR: Significant increases in mortality were noted for insects fed on the transgenic lines as compared to wild type plants, providing further support for RIPs having a role in plant resistance to insect pest species.