H
Haixue Zheng
Researcher at Civil Aviation Authority of Singapore
Publications - 136
Citations - 1616
Haixue Zheng is an academic researcher from Civil Aviation Authority of Singapore. The author has contributed to research in topics: Virus & Medicine. The author has an hindex of 17, co-authored 81 publications receiving 997 citations. Previous affiliations of Haixue Zheng include Chinese Academy of Sciences.
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Role of MicroRNAs in Hepatocellular Carcinoma.
TL;DR: Current findings are highlighted and recent work to determine the contribution of miRNA expression to the maintenance and growth of HCC is discussed, thereby providing a significant source of hope that miRNAs could serve as therapeutic targets.
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Foot-and-Mouth Disease Virus Viroporin 2B Antagonizes RIG-I-Mediated Antiviral Effects by Inhibition of Its Protein Expression
Zixiang Zhu,Guoqing Wang,Fan Yang,Weijun Cao,Ruoqing Mao,Xiaoli Du,Xiangle Zhang,Chuntian Li,Li Dan,Keshan Zhang,Hong-Bing Shu,Xiangtao Liu,Haixue Zheng +12 more
TL;DR: It is demonstrated that RIG-I could suppress FMDV replication during virus infection and identifies 2B as an antagonistic factor for F MDV to evade the antiviral response.
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G3BP1 inhibits RNA virus replication by positively regulating RIG-I-mediated cellular antiviral response
Wenping Yang,Yi Ru,Jingjing Ren,Juncui Bai,Junshu Wei,Shaozu Fu,Xiangtao Liu,Li Dan,Haixue Zheng +8 more
TL;DR: It is demonstrated that the Ras-GTPase-activating protein SH3-domain-binding protein 1 (G3BP1) serves as a positive regulator of the RIG-I-mediated signaling pathway and inhibited the replication of Sendai virus and vesicular stomatitis virus, indicating a positive regulation of G3 BP1 to cellular antiviral responses.
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Emergence of novel Seneca Valley virus strains in China, 2017.
TL;DR: The identification of novel SVV KS15-01-like strains showing a notable distinction with previous Chinese SVV strains are determined, implying the increased epidemic regions and potential threat to local pig breeds of SVV in China.
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Seneca Valley Virus 3Cpro abrogates the IRF3- and IRF7-mediated innate immune response by degrading IRF3 and IRF7.
TL;DR: It is shown that SVV 3Cpro reduces IRF3 and IRF7 protein expression level and phosphorylation and blocks the transcription ofIFN-β, IFN-α1, IFn-α4, and ISG54.