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Xiangle Zhang
Publications - 23
Citations - 604
Xiangle Zhang is an academic researcher. The author has contributed to research in topics: Virus & Viral replication. The author has an hindex of 11, co-authored 21 publications receiving 415 citations.
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Journal ArticleDOI
Role of MicroRNAs in Hepatocellular Carcinoma.
TL;DR: Current findings are highlighted and recent work to determine the contribution of miRNA expression to the maintenance and growth of HCC is discussed, thereby providing a significant source of hope that miRNAs could serve as therapeutic targets.
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Foot-and-Mouth Disease Virus Viroporin 2B Antagonizes RIG-I-Mediated Antiviral Effects by Inhibition of Its Protein Expression
Zixiang Zhu,Guoqing Wang,Fan Yang,Weijun Cao,Ruoqing Mao,Xiaoli Du,Xiangle Zhang,Chuntian Li,Li Dan,Keshan Zhang,Hong-Bing Shu,Xiangtao Liu,Haixue Zheng +12 more
TL;DR: It is demonstrated that RIG-I could suppress FMDV replication during virus infection and identifies 2B as an antagonistic factor for F MDV to evade the antiviral response.
Journal ArticleDOI
Review of Seneca Valley Virus: A Call for Increased Surveillance and Research.
Xiangle Zhang,Zixiang Zhu,Fan Yang,Weijun Cao,Tian Hong,Zhang Keshan,Haixue Zheng,Xiangtao Liu +7 more
TL;DR: Current knowledge concerning SVV infection, epidemiology, pathogenicity, immune response, and diagnostic methods are presented to aid the design and adoption of effective prevention and control strategies to counter this viral pathogen.
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The laboratory of genetics and physiology 2: emerging insights into the controversial functions of this RIG-I-like receptor.
TL;DR: A brief overview of L GP2 structure and functions is provided, with an expanded discussion on the regulation mechanisms in response to viral infection, hopefully stimulating insight into the divergent roles of LGP2 in the regulation of antiviral immune responses.
Journal ArticleDOI
Foot-and-mouth disease virus infection inhibits LGP2 protein expression to exaggerate inflammatory response and promote viral replication.
Zixiang Zhu,Chuntian Li,Xiaoli Du,Guoqing Wang,Weijun Cao,Fan Yang,Huanhuan Feng,Xiangle Zhang,Shi Zhengwang,Huanan Liu,Hong Tian,Li Dan,Keshan Zhang,Xiangtao Liu,Haixue Zheng +14 more
TL;DR: The antiviral role of LGP2 against F MDV is demonstrated and a novel antagonistic mechanism of FMDV that is mediated by 2B protein is described.