Hani Al-Salami

TL;DR: The role that the epithelial barrier plays in the pathophysiology of IBD as well as the major cytokines involved are investigated and the recent research that aims to develop new therapies for such chronic disorders is provided.

TL;DR: A number of novel techniques including layer-by-layer coating, self-polymerisation of shell, nanocomposite microparticulate drug delivery system seem to be promising for enhancing the oral bioavailability of insulin.

TL;DR: The structure and physiological function of insulin nanoparticle, as well as the efficiency and shortcomings, are examined, and some future directions and challenges to be addressed for the success of oral delivery of insulin‐loaded nanoparticle formulation are addressed.

TL;DR: Bile acids may improve bioavailability of drugs whose absorption-limiting factors include either poor aqueous solubility or low membrane permeability, and may withstand the gastrointestinal impediments and aid in the transporter-mediated absorption of physically complexed or chemically conjugated drug molecules.

TL;DR: The probiotic treatment of diabetic rats increases gliclazide bioavailability and lowers blood glucose levels by insulin-independent mechanisms, suggesting that the administration of probiotics may be beneficial as adjunct therapy in the treatment of diabetes.