R
Rebecca Negrulj
Researcher at Curtin University
Publications - 35
Citations - 1438
Rebecca Negrulj is an academic researcher from Curtin University. The author has contributed to research in topics: Bile acid & Ursodeoxycholic acid. The author has an hindex of 23, co-authored 33 publications receiving 1188 citations.
Papers
More filters
Journal ArticleDOI
Inflammatory bowel disease: clinical aspects and treatments.
TL;DR: The role that the epithelial barrier plays in the pathophysiology of IBD as well as the major cytokines involved are investigated and the recent research that aims to develop new therapies for such chronic disorders is provided.
Journal ArticleDOI
Stability and Release Kinetics of an Advanced Gliclazide-Cholic Acid Formulation: The Use of Artificial-Cell Microencapsulation in Slow Release Targeted Oral Delivery of Antidiabetics
Armin Mooranian,Rebecca Negrulj,Sangeetha Mathavan,Jorge Martinez,Jessica Sciarretta,Nigel Chen-Tan,Trilochan Mukkur,Momir Mikov,Momir Mikov,Mladena Lalić-Popović,M. Stojancevic,Svetlana Goločorbin-Kon,Svetlana Goločorbin-Kon,Hani Al-Salami +13 more
TL;DR: The new formulation of gliclazide-cholic acid (G-CA) exhibits colon-targeted delivery and the addition of CA prolonged G release suggesting its suitability for the sustained and targeted delivery of G and CA to the lower intestine.
Journal ArticleDOI
Microencapsulation as a novel delivery method for the potential antidiabetic drug, Probucol
Armin Mooranian,Rebecca Negrulj,Nigel Chen-Tan,Hesham S. Al-Sallami,Zhongxiang Fang,Trilochan Mukkur,Momir Mikov,Svetlana Goločorbin-Kon,Marc Fakhoury,Gerald F. Watts,Vance B. Matthews,Frank Arfuso,Hani Al-Salami +12 more
TL;DR: The new PB-SA microcapsules have good structural properties and may be suitable for the oral delivery of PB in T2D and are supported by differential scanning calorimetric analysis and Fourier transform infrared spectral studies, suggesting microcapsule stability.
Journal ArticleDOI
An advanced microencapsulated system: a platform for optimized oral delivery of antidiabetic drug-bile acid formulations.
Armin Mooranian,Rebecca Negrulj,Sangeetha Mathavan,Jorge Martinez,Jessica Sciarretta,Nigel Chen-Tan,Trilochan Mukkur,Momir Mikov,Mladena Lalić-Popović,M. Stojancevic,Svetlana Goločorbin-Kon,Hani Al-Salami +11 more
TL;DR: The new microencapsulated-formulation of G–CA with uniform and coherent structure has good and uniform structural properties and may be suitable for oral delivery of antidiabetic-bile acid formulations.
Journal ArticleDOI
Characterization of a novel bile acid-based delivery platform for microencapsulated pancreatic β-cells
TL;DR: Findings suggest potential benefits of the bile acid UDCA in β-cell microencapsulation and investigate the effect of UDCA on the morphology, swelling, stability, and size of these new microcapsules.