H
Hiroshi Saito
Researcher at University of Kentucky
Publications - 241
Citations - 11898
Hiroshi Saito is an academic researcher from University of Kentucky. The author has contributed to research in topics: Cancer & Lung cancer. The author has an hindex of 44, co-authored 235 publications receiving 10769 citations. Previous affiliations of Hiroshi Saito include Mitsubishi Heavy Industries & Harvard University.
Papers
More filters
Journal ArticleDOI
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial
Tetsuya Mitsudomi,Satoshi Morita,Yasushi Yatabe,Shunichi Negoro,Isamu Okamoto,Junji Tsurutani,Takashi Seto,Miyako Satouchi,Hirohito Tada,Tomonori Hirashima,Kazuhiro Asami,Nobuyuki Katakami,Minoru Takada,Hiroshige Yoshioka,Kazuhiko Shibata,Shinzoh Kudoh,Eiji Shimizu,Hiroshi Saito,Shinichi Toyooka,Kazuhiko Nakagawa,Masahiro Fukuoka +20 more
TL;DR: In this article, an open label, phase 3 study (WJTOG3405) with recruitment between March 31, 2006, and June 22, 2009, at 36 centers in Japan was conducted.
Journal ArticleDOI
Randomized Phase III Trial of Fluorouracil Alone Versus Fluorouracil Plus Cisplatin Versus Uracil and Tegafur Plus Mitomycin in Patients With Unresectable, Advanced Gastric Cancer: The Japan Clinical Oncology Group Study (JCOG9205)
Atsushi Ohtsu,Yasuhiro Shimada,Kuniaki Shirao,Narikazu Boku,Ichinosuke Hyodo,Hiroshi Saito,Noboru Yamamichi,Yoshinori Miyata,Nobumasa Ikeda,Seiichiro Yamamoto,Haruhiko Fukuda,Shigeaki Yoshida +11 more
TL;DR: Neither investigational regimen, FP nor UFTM, showed a survival advantage as compared with FU alone, althoughFP will remain a reference arm in a future trial for advanced gastric cancer.
Journal ArticleDOI
The Japanese guidelines for gastric cancer screening
Chisato Hamashima,Daisuke Shibuya,Hideo Yamazaki,Kazuhiko Inoue,Akira Fukao,Hiroshi Saito,Tomotaka Sobue +6 more
TL;DR: A guideline for gastric cancer screening using photofluorography is recommended for population-based and opportunistic screening in Japan based on the previously established method.
Journal ArticleDOI
Sensitivity and specificity of mammography and adjunctive ultrasonography to screen for breast cancer in the Japan Strategic Anti-cancer Randomized Trial (J-START): a randomised controlled trial
Noriaki Ohuchi,Akihiko Suzuki,Tomotaka Sobue,Masaaki Kawai,Seiichiro Yamamoto,Ying-Fang Zheng,Yoko Narikawa Shiono,Hiroshi Saito,Shinichi Kuriyama,Eriko Tohno,Tokiko Endo,Akira Fukao,Ichiro Tsuji,Takuhiro Yamaguchi,Yasuo Ohashi,Mamoru Fukuda,Takanori Ishida +16 more
TL;DR: Adjunctive ultrasonography increases sensitivity and detection rate of early cancers in asymptomatic women and reduces mortality in young women or women with dense breasts.
Journal ArticleDOI
Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice
Tetsuji Naka,Tomoshige Matsumoto,Masashi Narazaki,Minoru Fujimoto,Yoshiaki Morita,Yoshiyuki Ohsawa,Hiroshi Saito,Takashi Nagasawa,Yasuo Uchiyama,Tadamitsu Kishimoto +9 more
TL;DR: Findings suggest that SSI-1 prevents apoptosis by inhibiting the expression of Bax, and among various pro- and anti-apoptotic molecules examined, an up-regulation of BAX was found in lymphocytes of the spleen and thymus of SSI.