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Jacques Bille

Researcher at University of Lausanne

Publications -  244
Citations -  27030

Jacques Bille is an academic researcher from University of Lausanne. The author has contributed to research in topics: Fluconazole & Candida albicans. The author has an hindex of 80, co-authored 241 publications receiving 25458 citations. Previous affiliations of Jacques Bille include University Hospital of Lausanne.

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Revised Definitions of Invasive Fungal Disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group

TL;DR: These revised definitions of invasive fungal disease are intended to advance clinical and epidemiological research and may serve as a useful model for defining other infections in high-risk patients.
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Voriconazole Therapeutic Drug Monitoring in Patients with Invasive Mycoses Improves Efficacy and Safety Outcomes

TL;DR: Voriconazole therapeutic drug monitoring improves the efficacy and safety of therapy in severely ill patients with invasive mycoses and aids in prompt and complete neurological recovery.
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Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.

TL;DR: It is found that overexpression of the gene encoding 14DM either by gene amplification or by gene deregulation was not the major cause of resistance among these clinical isolates of fluconazole-resistant C. albicans, and that resistance could be mediated by energy-requiring efflux pumps such as ATP-binding cassette (ABC) multidrug transporters.