D
David W. Denning
Researcher at University of Manchester
Publications - 793
Citations - 75671
David W. Denning is an academic researcher from University of Manchester. The author has contributed to research in topics: Aspergillosis & Chronic pulmonary aspergillosis. The author has an hindex of 113, co-authored 736 publications receiving 66604 citations. Previous affiliations of David W. Denning include Manchester Academic Health Science Centre & University of Salford.
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Journal ArticleDOI
Revised Definitions of Invasive Fungal Disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group
Ben E. De Pauw,Thomas J. Walsh,J. Peter Donnelly,David A. Stevens,John E. Edwards,Thierry Calandra,Peter G. Pappas,Johan Maertens,Olivier Lortholary,Carol A. Kauffman,David W. Denning,Thomas F. Patterson,Georg Maschmeyer,Jacques Bille,William E. Dismukes,Raoul Herbrecht,William W. Hope,Christopher C. Kibbler,Bart Jan Kullberg,Kieren A. Marr,Patricia Muñoz,Frank C. Odds,John R. Perfect,Angela Restrepo,Markus Ruhnke,Brahm H. Segal,Jack D. Sobel,Tania C. Sorrell,Claudio Viscoli,John R. Wingard,Theoklis E. Zaoutis,John E. Bennett +31 more
TL;DR: These revised definitions of invasive fungal disease are intended to advance clinical and epidemiological research and may serve as a useful model for defining other infections in high-risk patients.
Journal ArticleDOI
Hidden Killers: Human Fungal Infections
Gordon D. Brown,David W. Denning,Neil A. R. Gow,Stuart M. Levitz,Mihai G. Netea,Theodore C. White +5 more
TL;DR: The importance of fungi as human pathogens is highlighted and the challenges the authors face in combating the devastating invasive infections caused by these microorganisms are discussed, in particular in immunocompromised individuals.
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Voriconazole versus Amphotericin B for Primary Therapy of Invasive Aspergillosis
Raoul Herbrecht,David W. Denning,David W. Denning,Thomas F. Patterson,John E. Bennett,Reginald Greene,Reginald Greene,J. W. Oestmann,Winfried V. Kern,Winfried V. Kern,Winfried V. Kern,Kieren A. Marr,Patricia Ribaud,Olivier Lortholary,Richard J. Sylvester,Robert H. Rubin,John R. Wingard,Paul Stark,Christine Durand,Denis Caillot,Eckhard Thiel,Pranatharthi H. Chandrasekar,Michael R. Hodges,Haran T. Schlamm,Peter F. Troke,Ben E. De Pauw +25 more
TL;DR: In patients with invasive aspergillosis,Initial therapy with voriconazole led to better responses and improved survival and resulted in fewer severe side effects than the standard approach of initial therapy with amphotericin B.
Journal ArticleDOI
Treatment of Aspergillosis: Clinical Practice Guidelines of the Infectious Diseases Society of America
Thomas J. Walsh,Elias Anaissie,David W. Denning,Raoul Herbrecht,Dimitrios P. Kontoyiannis,Kieren A. Marr,Vicki A. Morrison,Vicki A. Morrison,Brahm H. Segal,William J. Steinbach,David A. Stevens,David A. Stevens,Jo Anne H. Van Burik,John R. Wingard,Thomas F. Patterson +14 more
TL;DR: This research presents a novel, scalable, scalable and scalable approach that allows for real-time evaluation of the impact of Epstein-Barr virus on the development and management of childhood cancer in rats.
Journal ArticleDOI
Defining Opportunistic Invasive Fungal Infections in Immunocompromised Patients with Cancer and Hematopoietic Stem Cell Transplants: An International Consensus
Sibel Ascioglu,John H. Rex,B.E. de Pauw,John E. Bennett,J. Bille,F. Crokaert,David W. Denning,J.P. Donnelly,J. E. Edwards,Z. Erjavec,D. Fiere,O. Lortholary,Johan Maertens,Jacques F. Meis,Thomas F. Patterson,J. Ritter,D. Selleslag,Palak Shah,David A. Stevens,Thomas J. Walsh +19 more
TL;DR: A set of research-oriented definitions for the IFIs most often seen and studied in immunocompromised patients with cancer is proposed and three levels of probability are proposed: "proven," "probable," and "possible."