J
James H.-C. Wang
Researcher at University of Pittsburgh
Publications - 158
Citations - 11454
James H.-C. Wang is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Tendon & Tendinopathy. The author has an hindex of 54, co-authored 157 publications receiving 10136 citations. Previous affiliations of James H.-C. Wang include Washington University in St. Louis & University of Cincinnati.
Papers
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Journal ArticleDOI
Mechanobiology of tendon
TL;DR: The discussion begins with the mechanical forces acting on tendons in vivo, tendon structure and composition, and its mechanical properties, followed by a discussion of tendon healing and the role of mechanical loading and fibroblast contraction in tissue healing.
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An introductory review of cell mechanobiology.
James H.-C. Wang,B P. Thampatty +1 more
TL;DR: Future research in the area of cell mechanobiology will require novel experimental and theoretical methodologies to determine the type and magnitude of the forces experienced at the cellular and sub-cellular levels and to identify the force sensors/receptors that initiate the cascade of cellular and molecular events.
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Fibroblasts and Myofibroblasts in Wound Healing: Force Generation and Measurement
Bin Li,James H.-C. Wang +1 more
TL;DR: Understanding how forces are generated in these cells and knowing exactly how much force they produce may guide the development of optimal protocols for more effective treatment of tissue wounds in clinical settings.
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Specificity of endothelial cell reorientation in response to cyclic mechanical stretching
TL;DR: Human aortic endothelial cells respond very specifically to the type of deformation imposed upon them, and the extent of cell reorientation was more closely related to the stretching magnitude than the stretching rate.
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Characterization of differential properties of rabbit tendon stem cells and tenocytes
Jianying Zhang,James H.-C. Wang +1 more
TL;DR: TSCs exhibit distinct properties compared to tenocytes, including differences in cell marker expression, proliferative and differentiation potential, and cell morphology in culture.