J
Jennifer L. West
Researcher at Duke University
Publications - 283
Citations - 40210
Jennifer L. West is an academic researcher from Duke University. The author has contributed to research in topics: Self-healing hydrogels & Nanoshell. The author has an hindex of 92, co-authored 270 publications receiving 37641 citations. Previous affiliations of Jennifer L. West include University of Arizona & University of Texas at Austin.
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Journal ArticleDOI
Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
Leon R. Hirsch,R.J. Stafford,James A. Bankson,S.R. Sershen,Belinda Rivera,Roger E. Price,John D. Hazle,Nancy J. Halas,Jennifer L. West +8 more
TL;DR: In vivo studies under magnetic resonance guidance revealed that exposure to low doses of NIR light in solid tumors treated with metal nanoshells reached average maximum temperatures capable of inducing irreversible tissue damage, and found good correlation with histological findings.
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Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles.
TL;DR: A simple, non-invasive procedure that takes advantage of the strong near infrared (NIR) absorption of nanoshells, a new class of gold nanoparticles with tunable optical absorptivities that can undergo passive extravasation from the abnormal tumor vasculature due to their nanoscale size.
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Immunotargeted nanoshells for integrated cancer imaging and therapy
TL;DR: Immunotargeted nanoshells are engineered to both scatter light in the NIR enabling optical molecular cancer imaging and to absorb light, allowing selective destruction of targeted carcinoma cells through photothermal therapy.
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Photopolymerizable hydrogels for tissue engineering applications.
Kytai T. Nguyen,Jennifer L. West +1 more
TL;DR: Advantages of photopolymerization of hydrogels are presented, the photoinitiators and materials in current use are described and the applications that have been investigated are summarized.
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Near-Infrared Resonant Nanoshells for Combined Optical Imaging and Photothermal Cancer Therapy
TL;DR: Metal nanoshells were designed that possess both absorption and scattering properties in the NIR to provide optical contrast for improved diagnostic imaging and, at higher light intensity, rapid heating for photothermal therapy.