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Jiwei Liu

Researcher at Dalian Medical University

Publications -  34
Citations -  5103

Jiwei Liu is an academic researcher from Dalian Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 5, co-authored 8 publications receiving 4328 citations.

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USP22 regulates lipidome accumulation by stabilizing PPARγ in hepatocellular carcinoma

TL;DR: In this article , the ubiquitin-specific protease 22 (USP22) was identified as a key regulator for de novo fatty acid synthesis, which directly interacts with deubiquitinates and stabilizes peroxisome proliferator-activated receptor gamma (PPARγ) through K48-linked deUBiquitination, and in turn this stabilization increases acetyl-CoA carboxylase (ACC) and ATP citrate lyase (ACLY) expressions.