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John J. Lewin

Researcher at Johns Hopkins University

Publications -  34
Citations -  1453

John J. Lewin is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Sedation & Intensive care. The author has an hindex of 16, co-authored 34 publications receiving 1194 citations. Previous affiliations of John J. Lewin include University of Maryland, Baltimore & Johns Hopkins University School of Medicine.

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Glucocorticoid therapy in neurologic critical care.

TL;DR: The efficacy of glucocorticoid therapy for spinal cord injury is well established in ameliorating edema associated with brain tumors and in improving outcome in subsets of patients with bacterial meningitis.
Journal ArticleDOI

Update in the diagnosis and management of central nervous system infections.

TL;DR: New insights into the role of inflammation and the immune response in CNS infections have contributed to development of new diagnostic strategies using markers of inflammation, and to the study of agents with focused immunomodulatory activity, which may lead to further adjunctive therapy in human disease.
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Cognitive improvement during continuous sedation in critically ill, awake and responsive patients: the Acute Neurological ICU Sedation Trial (ANIST).

TL;DR: ICU patients may be offered sedation without necessarily compromising arousal or cognition if overt forebrain dysfunction is avoided, and higher ACE scores with DEX may be a consequence of the intellect-sparing yet calming effect of this drug.