Alejandro A. Rabinstein

TL;DR: These guidelines supersede the prior 2007 guidelines and 2009 updates and support the overarching concept of stroke systems of care and detail aspects of stroke care from patient recognition; emergency medical services activation, transport, and triage; through the initial hours in the emergency department and stroke unit.

TL;DR: These guidelines detail prehospital care, urgent and emergency evaluation and treatment with intravenous and intra-arterial therapies, and in-hospital management, including secondary prevention measures that are appropriately instituted within the first 2 weeks.

TL;DR: Evidence-based guidelines are presented for the care of patients presenting with aneurysmal subarachnoid hemorrhage and offer a framework for goal-directed treatment of the patient with aSAH.

TL;DR: Recommendations were developed based on literature review using the GRADE system, discussion integrating the literature with the collective experience of the participants and critical review by an impartial jury and emphasis was placed on the principle that recommendations should be based not only on the quality of the data but also tradeoffs and translation into practice.

TL;DR: I alteplase treatment should be administered within 3 hours of acute ischemic stroke in appropriate patients and should not be delayed while waiting for hematologic or coagulation testing if there is no reason to suspect an abnormal test.