J
Jon D. Heather
Researcher at Hammersmith Hospital
Publications - 23
Citations - 6947
Jon D. Heather is an academic researcher from Hammersmith Hospital. The author has contributed to research in topics: Cerebral blood flow & Positron emission tomography. The author has an hindex of 19, co-authored 23 publications receiving 6822 citations.
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Journal ArticleDOI
Spatial registration and normalization of images
Karl J. Friston,John Ashburner,Chris D. Frith,Jean-Baptiste Poline,Jon D. Heather,Richard S. J. Frackowiak +5 more
TL;DR: A general technique that facilitates nonlinear spatial (stereotactic) normalization and image realignment is presented that minimizes the sum of squares between two images following non linear spatial deformations and transformations of the voxel (intensity) values.
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Quantitative measurement of regional cerebral blood flow and oxygen metabolism in man using 15O and positron emission tomography: theory, procedure, and normal values.
TL;DR: The method appears suitable for the study of human cerebral aerobic metabolism and blood flow under differing physiological conditions and in a wide variety of neurological disorders.
Journal ArticleDOI
Localisation in PET images: direct fitting of the intercommissural (AC-PC) line.
Karl J. Friston,Richard E. Passingham,Richard E. Passingham,J. G. Nutt,J. G. Nutt,Jon D. Heather,G. V. Sawle,R. S. J. Frackowiak +7 more
TL;DR: A technique is described for estimating the position of the intercommisural line (AC–PC line) directly from landmarks on positron emission tomographic images, namely the ventral aspects of the anterior and posterior corpus callosum, the thalamus, and occipital pole, which showed minimal vertical and angular displacement when measured on magnetic resonance imaging (MRI) scans.
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Physical performance of the latest generation of commercial positron scanner
TL;DR: In this article, a study of some of the basic physical performance characteristics of an advanced commercial positron-emission tomograph (PET) is reported. But the performance of the PET was not analyzed.
Journal ArticleDOI
Measurement of regional cerebral blood flow and oxygen utilisation in patients with cerebral tumours using 15O and positron emission tomography: analytical techniques and preliminary results.
M. Ito,M. Ito,Adriaan A. Lammertsma,Richard J. S. Wise,Silvia Bernardi,Richard S. J. Frackowiak,Jon D. Heather,C. G. McKenzie,D. G. T. Thomas,Terry Jones +9 more
TL;DR: A relative uncoupling between oxygen consumption and blood flow was observed in all tumours as indicated by a decreased regional fractional extraction of oxygen (rOER), which suggests that a major proportion of these tumours had sufficient blood supply to meet oxygen metabolic demand.