J
José L. Martínez
Researcher at Spanish National Research Council
Publications - 274
Citations - 24023
José L. Martínez is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Antibiotic resistance & Efflux. The author has an hindex of 70, co-authored 236 publications receiving 19897 citations. Previous affiliations of José L. Martínez include University of Wisconsin-Madison & Autonomous University of Madrid.
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Natural Antibiotic Resistance and Contamination by Antibiotic Resistance Determinants: The Two Ages in the Evolution of Resistance to Antimicrobials
TL;DR: The study of antibiotic resistance has been historically concentrated on the analysis of bacterial pathogens and on the consequences of acquiring resistance for human health, but the studies on antibiotic resistance should not be confined to clinical-associated ecosystems.
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Antibiotics and antibiotic resistance genes in natural environments.
TL;DR: The large majority of antibiotics currently used for treating infections and the antibiotic resistance genes acquired by human pathogens each have an environmental origin and the function of these elements in their environmental reservoirs may be very distinct from the “weapon-shield” role they play in clinical settings.
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Environmental pollution by antibiotics and by antibiotic resistance determinants
TL;DR: The impact that pollution by antibiotics or by antibiotic resistance genes may have for both human health and for the evolution of environmental microbial populations is reviewed.
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Tackling antibiotic resistance: the environmental framework
Thomas U. Berendonk,Célia M. Manaia,Christophe Merlin,Despo Fatta-Kassinos,Eddie Cytryn,Fiona Walsh,Helmut Bürgmann,Henning Sørum,Madelaine Norström,Marie-Noëlle Pons,Norbert Kreuzinger,Pentti Huovinen,Stefania Stefani,Thomas Schwartz,Veljo Kisand,Fernando Baquero,José L. Martínez +16 more
TL;DR: The main knowledge gaps, the future research needs and the policy and management options that should be prioritized to tackle antibiotic resistance in the environment are discussed.
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What is a resistance gene? Ranking risk in resistomes.
TL;DR: Rules are proposed for estimating the risks associated with genes that are present in environmental resistomes by evaluating the likelihood of their introduction into human pathogens, and the consequences of such events for the treatment of infections.