Natural Antibiotic Resistance and Contamination by Antibiotic Resistance Determinants: The Two Ages in the Evolution of Resistance to Antimicrobials
TLDR
The study of antibiotic resistance has been historically concentrated on the analysis of bacterial pathogens and on the consequences of acquiring resistance for human health, but the studies on antibiotic resistance should not be confined to clinical-associated ecosystems.Abstract:
Work in our laboratory is supported by grants BIO2008-00090 from the Spanish Ministry of Science and Innovation and KBBE-227258 (BIOHYPO), HEALTH-F3-2011-282004 (EVOTAR), and HEALTH-F3-2010-241476 (PAR) from European Union.read more
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The Microbial Efficiency-Matrix Stabilization (MEMS) framework integrates plant litter decomposition with soil organic matter stabilization: do labile plant inputs form stable soil organic matter?
TL;DR: It is proposed that labile plant constituents are the dominant source of microbial products, relative to input rates, because they are utilized more efficiently by microbes, and become the main precursors of stable SOM by promoting aggregation and through strong chemical bonding to the mineral soil matrix.
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Urban wastewater treatment plants as hotspots for the release of antibiotics in the environment: a review
I. Michael,Luigi Rizzo,Christa S. McArdell,Célia M. Manaia,Christophe Merlin,Thomas Schwartz,Christophe Dagot,Despo Fatta-Kassinos +7 more
TL;DR: The aim of the present paper is to critically review the fate and removal of various antibiotics in wastewater treatment, focusing on different processes (i.e. biological processes, advanced treatment technologies and disinfection) in view of the current concerns related to the induction of toxic effects in aquatic and terrestrial organisms.
Journal ArticleDOI
Effect of Essential Oils on Pathogenic Bacteria
TL;DR: The increasing resistance of microorganisms to conventional chemicals and drugs is a serious and evident worldwide problem that has prompted research into the identification of new biocides with broad activity.
Journal ArticleDOI
Keystone taxa as drivers of microbiome structure and functioning
TL;DR: A definition of keystone taxa in microbial ecology is proposed and over 200 microbial keystoneTaxa that have been identified in soil, plant and marine ecosystems, as well as in the human microbiome are summarized.
Journal ArticleDOI
The importance of anabolism in microbial control over soil carbon storage
TL;DR: This Perspective looks at how microbial anabolism and the soil microbial carbon pump control microbial necromass accumulation and stabilization; the ‘entombing effect’.
References
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Origins and Evolution of Antibiotic Resistance
Julian Davies,Dorothy Davies +1 more
TL;DR: A review of antibiotic resistance development over the past half-century can be found in this article, with the oft-restated conclusion that it is time to act and to restore the therapeutic applications of antibiotics.
Journal ArticleDOI
Exaptation; a missing term in the science of form
TL;DR: This work presents several examples of exaptation, indicating where a failure to concep- tualize such an idea limited the range of hypotheses previously available, and proposes a terminological solution to the problem of preadaptation.
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Antibiotic resistance is ancient
Vanessa M. D'Costa,Christine E. King,Lindsay Kalan,Mariya Morar,Wilson W L Sung,Carsten Schwarz,Duane G. Froese,Grant D. Zazula,Fabrice Calmels,Régis Debruyne,G. Brian Golding,Hendrik N. Poinar,Gerard D. Wright +12 more
TL;DR: Target metagenomic analyses of rigorously authenticated ancient DNA from 30,000-year-old Beringian permafrost sediments are reported and show conclusively that antibiotic resistance is a natural phenomenon that predates the modern selective pressure of clinical antibiotic use.
Journal ArticleDOI
Heavy use of prophylactic antibiotics in aquaculture: a growing problem for human and animal health and for the environment
TL;DR: Global efforts are needed to promote more judicious use of prophylactic antibiotics in aquaculture as accumulating evidence indicates that unrestricted use is detrimental to fish, terrestrial animals, and human health and the environment.
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Antibiotics and antibiotic resistance in water environments
TL;DR: Methods to reduce resistant bacterial load in wastewaters, and the amount of antimicrobial agents, in most cases originated in hospitals and farms, include optimization of disinfection procedures and management of wastewater and manure.
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