J
Judith L. Rapoport
Researcher at National Institutes of Health
Publications - 36
Citations - 10691
Judith L. Rapoport is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Schizophrenia & Psychosis. The author has an hindex of 27, co-authored 36 publications receiving 10191 citations. Previous affiliations of Judith L. Rapoport include Georgetown University.
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Journal ArticleDOI
Brain development during childhood and adolescence: a longitudinal MRI study.
Jay N. Giedd,Jonathan D. Blumenthal,Neal Jeffries,F X Castellanos,Hong Liu,Alex P. Zijdenbos,Tomáš Paus,Alan C. Evans,Judith L. Rapoport +8 more
TL;DR: This large-scale longitudinal pediatric neuroimaging study confirmed linear increases in white matter, but demonstrated nonlinear changes in cortical gray matter, with a preadolescent increase followed by a postadolescent decrease.
Journal ArticleDOI
Intellectual ability and cortical development in children and adolescents
Philip Shaw,Dede Greenstein,Jason P. Lerch,Liv S. Clasen,Rhoshel K. Lenroot,Nitin Gogtay,Alan C. Evans,Judith L. Rapoport,Jay N. Giedd +8 more
TL;DR: This study indicates that the neuroanatomical expression of intelligence in children is dynamic, and finds a marked developmental shift from a predominantly negative correlation between intelligence and cortical thickness in early childhood to a positive correlation in late childhood and beyond.
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Mapping adolescent brain change reveals dynamic wave of accelerated gray matter loss in very early-onset schizophrenia
Paul M. Thompson,Christine N. Vidal,Jay N. Giedd,Peter Gochman,Jonathan D. Blumenthal,Rob Nicolson,Arthur W. Toga,Judith L. Rapoport +7 more
TL;DR: Brain mapping algorithms detected striking anatomical profiles of accelerated gray matter loss in very early-onset schizophrenia; surprisingly, deficits moved in a dynamic pattern, enveloping increasing amounts of cortex throughout adolescence.
Journal ArticleDOI
Childhood-onset schizophrenia: A double-blind clozapine-haloperidol comparison
Sanjiv Kumra,Jean A. Frazier,Leslie K. Jacobsen,Kathleen McKenna,Charles T. Gordon,Marge C. Lenane,Susan D. Hamburger,Amy Smith,Kathleen E. Albus,Javad Alaghband-Rad,Judith L. Rapoport +10 more
TL;DR: In this article, the efficacy and adverse effects of clozapine and haloperidol were compared for children and adolescents with early-onset schizophrenia in a 6-week double-blind parallel comparison.
Journal ArticleDOI
Genetic variation at the 22q11 PRODH2/DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia
Hui Liu,Simon C. Heath,Christina Sobin,J. Louw Roos,Brandi L. Galke,Maude L. Blundell,Marge Lenane,B. A. Robertson,Ellen M. Wijsman,Judith L. Rapoport,Joseph A. Gogos,Maria Karayiorgou +11 more
TL;DR: In three independent samples, evidence is provided for a contribution of the PRODH2/DGCR6 locus in 22q11-associated schizophrenia and an unusual pattern of PRODh2 gene variation that mimics the sequence of a linked pseudogene is uncovered.