K
Karsten König
Researcher at Saarland University
Publications - 363
Citations - 13193
Karsten König is an academic researcher from Saarland University. The author has contributed to research in topics: Laser & Autofluorescence. The author has an hindex of 58, co-authored 354 publications receiving 12347 citations. Previous affiliations of Karsten König include Schiller International University & University of Jena.
Papers
More filters
Journal ArticleDOI
Multiphoton microscopy in life sciences
TL;DR: Owing to the high NIR penetration depth, non‐invasive optical biopsies can be obtained from patients and ex vivo tissue by morphological and functional fluorescence imaging of endogenous fluorophores such as NAD(P)H, flavin, lipofuscin, porphyrins, collagen and elastin.
Journal ArticleDOI
Targeted transfection by femtosecond laser.
Uday K. Tirlapur,Karsten König +1 more
TL;DR: A variety of mammalian cells can be directly transfected with DNA without perturbing their structure by first creating a tiny, localized perforation in the membrane using ultrashort (femtosecond), high-intensity, near-infrared laser pulses.
Journal ArticleDOI
Fluorescence lifetime imaging by time‐correlated single‐photon counting
TL;DR: A time‐correlated single photon counting (TCPSC) technique that allows time‐resolved multi‐wavelength imaging in conjunction with a laser scanning microscope and a pulsed excitation source is presented.
Journal ArticleDOI
Impact of decellularization of xenogeneic tissue on extracellular matrix integrity for tissue engineering of heart valves.
Katja Schenke-Layland,O. Vasilevski,Florian Opitz,Karsten König,I. Riemann,Karl-Jürgen Halbhuber,Th. Wahlers,Ulrich A. Stock +7 more
TL;DR: The enzymatic decellularization process of heart valves revealed a time-dependent loss of cells, ECM components and biomechanical strength, suggesting ECM-integrity may be compromised with prolonged incubation.
Journal ArticleDOI
Clinical multiphoton tomography
TL;DR: This review reflects state of the art technology and reports on applications in the fields of early stage melanoma detection, skin aging, nanoparticle imaging, tissue engineering, and in situ screening of pharmaceutical and cosmetical products.